摘要
目的分析1990—2019年我国5种性传播感染(STIs)的流行病学负担及变化趋势。方法从2019全球疾病负担数据库获取我国及其他地区STIs发病、患病及伤残调整生命年(DALY)指标的估计数和标准化率,评估我国STIs的流行病学负担及变化趋势。结果2019年,STIs造成我国约2.42亿人患病,造成1.73亿新发病例和35万人年的DALY损失。与1990年相比,我国患病和发病人数分别增加了59.75%和30.02%,DALY数量下降了35.19%。1990—2019年,15~49岁中青年组衣原体感染和淋菌感染的发病率、生殖器疱疹和滴虫病的DALY率呈上升趋势。5种STIs中,滴虫病感染对女性造成的疾病负担远高于男性。随着社会人口学指数(SDI)的增加,我国STIs负担逐渐降低,在SDI超过0.65后,标化DALY率下降速度加快。结论我国STIs总体疾病负担在1990—2019年呈下降趋势,但15~49岁中青年的疾病负担最重,尤其在滴虫病和衣原体感染上。
Objective To analyze the epidemiological burden and change trend of five sexually transmitted infections(STIs)in China from 1990 to 2019.Methods The estimated numbers and standardized rates of STIs incidence,prevalence,and disability-adjusted life years(DALY)in China and other regions were obtained from the Global Burden of Disease Study 2019.The epidemic burden and change trend of STIs in China were compared and evaluated.Results In2019,STIs affected about 242 million people in China,resulting in 173 million new cases and 350000 person years of DALY losses.Compared with 1990,the prevalence and incidence of STIs increased by 59.75%and 30.02%,respectively,and the number of DALY decreased by 35.19%.From 1990 to 2019,the incidence rate of chlamydia infection and gonococcal infection in the young and middle-aged group(aged 15-49 years)showed an upward trend;in addition,the DALY rate of genital herpes and trichomoniasis also increased.Among the 5 STIs,the disease burden caused by trichomoniasis infection in women was much higher than that in men.With the increase in the socio-demographic index(SDI),the burden of STIs in China gradually decreased.After the SDI exceeded 0.65,the decline rate of standardized DALY rate sharply increased.Conclusion The disease burden of STIs in China shows a downward trend from 1990 to2019,and the disease burden of the young and middle-aged group(aged 15-49 years)is the most significant,especially in trichomoniasis and chlamydia infection.
作者
杨晓雨
陈东宇
王红心
樊文龙
潘素跃
胡敏
黄巧
王朴
何玉清
YANG Xiaoyu;CHEN Dongyu;WANG Hongxin;FAN Wenlong;PAN Suyue;HU Min;HUANG Qiao;WANG Pu;HE Yuqing(Institute of Medical Systems Biology,School of Public Health,Guangdong Medical University,Dongguan 523808,P.R.China)
出处
《中国循证医学杂志》
CSCD
北大核心
2022年第7期778-784,共7页
Chinese Journal of Evidence-based Medicine
基金
国家自然科学基金项目(编号:81773312)
广东省“扬帆计划引进紧缺拔尖”人才资助项目(编号:201433005)
2021年东莞市社会发展项目(编号:20211800904372)。
关键词
中国
性传播感染
伤残调整生命年
流行趋势
China
Sexually transmitted infection
Disability adjusted life year
Epidemiological trend
