摘要
目的:观察六味痔消膏外用治疗混合痔术后气滞血瘀型创缘水肿的临床疗效。方法:将混合痔术后气滞血瘀型创缘水肿患者100例,按照随机数字表法分成治疗组和对照组,每组各50例。治疗组采用六味痔消膏外用治疗,对照组采用九华膏外用治疗,均于排便坐浴后使用,2次/d,疗程均为10 d。观察比较2组治疗第1、4、6、10天创缘水肿体积评分、术口疼痛评分,记录2组创缘水肿消失时间、术口疼痛消失时间,并进行安全性评估。结果:实际纳入病例治疗组为41例,对照组为43例。治疗组治疗第7天及第10天创缘水肿评分、术口疼痛评分均低于对照组,差异有统计学意义(P<0.05或P<0.01),治疗组创缘水肿消失时间和术口疼痛消失时间均短于对照组,差异有统计学意义(P<0.05)。治疗组1例患者因出现肛周过敏性皮疹中止治疗并退出研究,且停药后皮疹消退,其他病例未出现不良反应。结论:六味痔消膏外用可促进混合痔术后气滞血瘀型创缘水肿的消退,具有良好疗效。
Objective: To investigate the clinical effect of external application of Liuwei Zhixiao ointment in the treatment of wound edge edema with Qi stagnation and blood stasis after surgery for mixed hemorrhoids.Methods: A total of 100 patients with wound edge edema with Qi stagnation and blood stasis after surgery for mixed hemorrhoids were divided into treatment group and control group using a random number table, with 50 patients in each group.The patients in the treatment group were given external application of Liuwei Zhixiao ointment, and those in the control group were given external application of Jiuhua ointment;the drugs were used after defecation and sitz bath, twice a day for 10 consecutive days.The two groups were compared in terms of wound edge edema volume score and incision pain score on days 1,4,6,and 10 of treatment, and the time to disappearance of wound edge edema and incision pain was recorded for both groups;a safety assessment was also performed.Results: A total of 41 patients in the treatment group and 43 patients in the control group were actually included in analysis.Compared with the control group, the treatment group had significantly lower wound edge edema score and incision pain score on days 7 and 10 of treatment(P<0.05 or P<0.01) and significantly shorter time to disappearance of wound edge edema and incision pain(P<0.05).In the treatment group, 1 patient discontinued treatment and withdrew from the study due to allergic rash in the perianal region, and disappearance of rash was observed after drug withdrawal, while this adverse event was not observed in the other patients.Conclusion: External application of Liuwei Zhixiao ointment can promote the resolution of wound edge edema with Qi stagnation and blood stasis after surgery for mixed hemorrhoids and thus has a marked therapeutic effect.
作者
钟腾芳
吴强
马辉
匡碧艳
ZHONG Tengfang;WU Qiang;MA Hui;KUANG Biyan(Liling Hospital of Traditional Chinese Medicine,Liling 412200,Hunan,China)
出处
《湖南中医杂志》
2022年第5期15-18,共4页
Hunan Journal of Traditional Chinese Medicine
基金
湖南省中医药科研计划项目(201975)。
关键词
混合痔
术后创缘水肿
气滞血瘀证
六味痔消膏
mixed hemorrhoids
postoperative wound edge edema
syndrome of Qi stagnation and blood stasis
Liuwei Zhixiao ointment
