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激素抵抗型肾病综合征采用参芪地黄汤加味的临床效果研究 被引量:2

Clinical Effect Research of Modified Ginseng-milkvetch Glutinous Rehmannia Decoction on Hormone Resistant Nephrotic Syndrome
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摘要 目的研究激素抵抗型肾病综合征采用参芪地黄汤加味的临床效果。方法选取我院在2017年7月-2019年6月收治106例激素抵抗型肾病综合征的患者,随机分为对照组和观察组各53例。对照组给予常规治疗。观察组给予常规治疗+参芪地黄汤加味治疗。对两组的临床生化指标、治疗效果和不良反应进行观察。结果观察组治疗后24h尿蛋白、血清白蛋白、血清超敏C反应蛋白、血清三酰甘油、血清总胆固醇、血清尿素氮、血肌酐、临床疗效和不良反应发生率显著好于对照组(P<0.05)。结论激素抵抗型肾病综合征采用参芪地黄汤加味疗效显著,可显著改善肾功能及症状体征,安全性好。 Objective To study clinical effect of modified ginseng-milkvetch glutinous rehmannia decoction on hormone resistant nephrotic syndrome.Methods The paper chose 106 patients with hormone resistant nephrotic syndrome treated in our hospital from July 2017 to June 2019,and divided them into control group and observation group randomly.Control group was treated with routine treatment,and observation group with routine treatment+modified ginseng-milkvetch glutinous rehmannia decoction.Clinical biochemical indexes,curative effect and adverse reactions between two groups were observed.Results 24 hours after treatment,urinary protein,serum albumin,serum highsensitivity C-reactive protein,serum triacylglycerol,serum total cholesterol,serum urea nitrogen,serum creatinine,clinical effect and incidence of adverse reactions in observation group was significantly better than control group(P<0.05).Conclusion Modified ginseng-milkvetch glutinous rehmannia decoction can achieve significant effect for hormone resistant nephrotic syndrome,improve renal function,symptoms and signs significantly with good safety.
作者 母淑娟 张颖 MU Shujuan;ZHANG Ying(Nephrology Department,Guanganmen Hospital,China Academy of Chinese Medical Sciences,Beijing,102600;Endocrinology Department,Guanganmen Hospital,China Academy of Chinese Medical Sciences,Beijing,102600)
出处 《智慧健康》 2022年第12期100-102,共3页 Smart Healthcare
关键词 激素抵抗型 肾病综合征 参芪地黄汤加味 Hormone resistant type Nephrotic syndrome Modified ginseng-milkvetch glutinous rehmannia decoction
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