摘要
小气道隶属于肺络系统中的气络部分,小气道结构功能的病变影响整个肺络系统以及肺生理功能的正常发挥。小气道阻塞是慢性阻塞性肺疾病的早期阶段,吸烟是其主要的危险因素之一。结合“毒”邪理论和络病学说,认为烟草烟雾是本病的使动因素,烟雾对小气道的影响包括介导气道炎症反应、黏液分泌和气道阻塞以及肺内组织损伤。烟毒伤络过程包括:留滞气络积蕴成毒阶段、成毒络损阶段和络损内生新毒阶段。治疗强调排毒通络、益气养阴,初期留滞气络积蕴成毒阶段宜清肺润络排毒,烟雾积聚成毒络损阶段宜益气通络排毒,络损内生新毒阶段宜逐瘀化痰通络。
Small airways belong to the qi collateral of the lung collaterals,and their damages may result in abnormalities of the entire lung collateral system,and its physiological functions.Small airways obstruction is the early stage of chronic obstructive pulmonary disease(COPD),for which smoking has been recognized as one of the main risk factors.Based on a combination of the theory of“toxic”pathogen and of pulmonary collateral diseases,this study proposes that tobacco smoke is the driving factor of this disease.The injury of lung collaterals by tobacco smoke is manifested in its effect on small airways,which mediates airway inflammation,mucus secretion and eventual obstruction of the passages.Tissue damage in the lungs are caused by smoke invading qi collaterals,which mainly involves the stages smoke evil accumulating in the qi collaterals until toxic levels,the smoke toxins inducing collateral damage,and new toxins result ing from the damaged collaterals.For the treatment,the focus should be placed on removing the toxins and unblocking the collaterals,tonifying qi and nourishing yin.At the initial stage,it is advisable to clear the lungs,moisten collaterals and expel the toxins.At the second stage,the key is to nourish qi and unblock the collaterals and remove the toxins.To deal with the new toxins generated in the third stage,it is suggested to remove stasis,dissolve phlegm and unblock the collaterals.
作者
赵艳芬
王琦
姜云宁
滕俊
李睿
杨天舒
张永生
ZHAO Yanfen;WANG Qi;JIANG Yunning;TENG Jun;LI Rui;YANG Tianshu;ZHANG Yongsheng(Beijing University of Chinese Medicine,Beijing 100029;Dongfang Hospital,Beijing University of Chinese Medicine)
出处
《现代中医临床》
2022年第3期43-47,共5页
Modern Chinese Clinical Medicine
基金
国家中医药管理局第五批全国中医优秀人才研修项目(国中医药办人教函[2022]1号)。
关键词
慢性阻塞性肺疾病
小气道阻塞
吸烟
毒损肺络
毒邪理论
络病学说
chronic obstructive pulmonary disease
small airway obstruction
smoking
toxic damage to lungs
the theory of“toxin”
the theory of collateral disease
