摘要
COPD病性本虚标实,本虚金水不固是COPD患者伏毒蕴肺的病理基础,反复感邪是引伏毒外发的主要致病因素,COPD稳定期关键病机是伏毒蕴藏,损伤肺之气络及血络。因此,金水相生、祛毒通络为COPD稳定期的核心治法。补肺汤既可金水相生以托毒透邪,也可祛毒通络令伏毒无所藏,切合COPD稳定期金水不固、伏毒损络之病机,且临床疗效颇佳。基于中医伏毒蕴肺病机,进一步认识并探析补肺汤治疗COPD稳定期相关机理,以期对临床有所裨益。
Chronic obstructive pulmonary disease(COPD)is characterized by excess in nature and deficiency in superficiality.For COPD patients,the deficiency of lung and kidney is the basis for production of the latent toxin,and repeated exogenous infection is the main factor for the latent toxin to enter the lung.The key pathogenesis of stable COPD is the entry of latent toxin into the lung and the injury of lung and collaterals.Therefore,tonifying lung and kidney,removing toxins and dredging collaterals are the core treatment methods for COPD in stable period.Bufei Decoction is with good efficacy in the treatment of COPD in stable period,which can not only tonify lung and kidney to consolidate,but also dredging collaterals to remove toxins.Based on the pathogenesis of"latent toxin entering lung",the relevant mechanisms of Bufei Decoction in treating stable COPD were further understood and explored,in order to benefit clinical practice.
作者
张雯
张琼
何沂
金沐阳
张新宇
周瑞玲
Zhang Wen;Zhang Qiong;He Yi;Jin Muyang;Zhang Xinyu;Zhou Ruiling(Department of Internal Medicine,Beijing Chaoyang District Hospital of Traditional Chinese Medicine,Beijing 100020,China;Department of Respiratory Medicine,Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China;Department of Surgery,Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China)
出处
《国际中医中药杂志》
2023年第11期1345-1349,共5页
International Journal of Traditional Chinese Medicine
基金
国家自然科学基金项目(81673817)
中国中医科学院科技创新工程重点项目(CI2021A01103)。
关键词
肺疾病
慢性阻塞性
伏毒
标本兼治
补肺汤
中医病机
Pulmonary disease,chronic obstructive
Latent Toxin
Simultaneous treatment of the symptoms and root cause
Bufei Decoction
Pathogenesis(TCM)
