摘要
目的分析整形保乳术联合腋窝淋巴结清扫术(ALNB)对乳腺癌患者疗效、ICBN保留成功率的影响及术后复发的危险因素。方法将162例的乳腺癌患者分为观察组和对照组,对照组患者采用改良根治术进行治疗,观察组患者采用整形保乳术,2组患者均行ALNB。统计患者临床资料和病理资料,记录患者标本体积、最小及最大手术切缘、并发症等治疗情况,记录患者术后复发情况;计算患者ICBN保留成功率;术后12个月对患者感觉功能、乳房美容效果客观评分进行评估。结果观察组患者切除体积、最小手术切缘和最大手术切缘明显小于对照组,感觉功能改善情况明显优于对照组,ICBN保留成功率和乳房美容效果客观评分明显高于对照组,且差异存统计学意义(P<0.05)。2组患者术后3年复发率无明显差异(P>0.05);复发与未复发患者年龄、肿瘤直径、肿瘤分期、淋巴结转移和分子分型存明显差异,且差异存在统计学意义(P<0.05);乳腺癌患者年龄、肿瘤直径、肿瘤分期、淋巴结转移、分子分型存是影响乳腺癌患者术后复发的独立性危险因素(P<0.05)。结论整形保乳术联合ALNB术可有效提高乳腺癌患者治疗效果和ICBN保留成功率。患者年龄、肿瘤直径、肿瘤分期、淋巴结转移、分子分型存是影响乳腺癌患者术后复发的独立性危险因素。
Objective To analyze the effect of plastic breast-conserving surgery combined with ALNB surgery on breast cancer patients,the effect of ICBN retention success rate and the risk factors of postoperative recurrence.Methods 162 breast cancer patients were divided into the observation group and the control group;patients in the control group were treated with modified radical surgery combined with ALNB surgery,and patients in the observation group were treated with plastic surgery and breast preservation Surgery combined with ALNB treatment;statistics of patients'clinical data and pathological data,records of patient specimen volume,minimum and maximum surgical margins,complications and other treatments,records of patients'postoperative recurrence;calculation of the patient's ICBN retention success rate;12 cases after surgery The patient's sensory function and breast beauty effect were evaluated objectively every month.Results The resection volume,minimum surgical margin and maximum surgical margin of the observation group were significantly less than those of the control group.The improvement of sensory function was significantly better than that of the control group.The ICBN retention success rate and the objective score of breast cosmetic effect were significantly higher than those of the control group.There was statistical significance(P<0.05);there was no significant difference in the recurrence rate of the 2 groups of patients 1 year after surgery(P>0.05);there were significant differences in age,tumor diameter,tumor stage,lymph node metastasis,and molecular classification between the 2 groups of patients without recurrence.And the difference was statistically significant(P<0.05);breast cancer patients'age,tumor diameter,tumor stage,lymph node metastasis,and molecular typing are independent threat factors that affect postoperative recurrence of breast cancer patients(P<0.05).Conclusion Plastic breast-conserving surgery combined with ALNB surgery can effectively improve the curative effect of breast cancer patie
作者
宋晓丹
赵北永
关华鹤
SONG Xiaodan;ZHAO Beiyong;GUAN Huahe(Zhoukou Central Hospital,Zhoukou,466000)
出处
《实用癌症杂志》
2022年第7期1215-1218,共4页
The Practical Journal of Cancer
基金
河南省医学科技公关项目(编号:201702176)。
关键词
整形保乳术
腋窝淋巴结清扫术
乳腺癌
ICBN保留成功率
术后复发
Plastic breast-conserving surgery
Axillary lymph node dissection
Breast cancer
ICBN retention success rate
Postoperative recurrence
