摘要
目的分析高度近视患者行有晶状体眼后房型人工晶状体(ICL)植入术后拱高的变化及其影响因素,并给出术后不同时间点拱高的预测方程。方法分析2020年8月至11月于徐州市第一人民医院眼科收治的拟行ICL植入术治疗高度近视的患者32例63眼的临床资料,术前记录患者的前房角度、前房深度、前房容积、角膜厚度、白到白间距(WTW)、睫状沟直径(STS)、术前等效球镜度和自然晶状体厚度,同时记录术中植入的ICL尺寸,使用Pentacam眼前节分析系统测量患眼术后1 d、1个月、6个月、12个月的拱高,分析上述观察指标对于术后拱高的影响。通过多元线性逐步回归分析,去除存在共性的变量,筛选出独立因素。以独立因素作为自变量,ICL术后拱高作为因变量,分析各因素对于ICL术后拱高的影响是否有统计学意义。结果本研究入组患者年龄为(26.59±5.73)岁,术后1个月拱高显著低于术后1 d,术后6个月拱高显著低于术后1个月,术后12个月拱高显著低于术后6个月,差异均有统计学意义(均为P<0.05)。多元线性逐步回归分析结果显示,前房深度和自然晶状体厚度均是高度近视患者ICL植入术后拱高的独立影响因素(均为P<0.05)。Spearman相关性分析结果显示,术后拱高与前房深度、前房容积和ICL尺寸均呈正相关,与自然晶状体厚度呈负相关(均为P<0.05)。影响高度近视患者ICL植入术后1 d、1个月、6个月、12个月拱高的回归方程分别为术后1 d拱高(μm)=258.226-435.606×自然晶状体厚度(mm)+291.971×前房深度(mm)+75.134×ICL尺寸(mm)+0.166×前房容积(mm^(3));术后1个月拱高(μm)=545.797-391.858×自然晶状体状厚度(mm)+221.224×前房深度(mm)+44.786×ICL尺寸(mm)+0.505×前房容积(mm^(3));术后6个月拱高(μm)=208.770-287.950×自然晶状体厚度(mm)+254.127×前房深度(mm)+30.280×ICL尺寸(mm)+0.619×前房容积(mm^(3));术后12个月拱高(μm)=0.999-251.694×自然晶状体
Objective To analyze the vault changes in patients with high myopia after the implantation of an implantable collamer lens(ICL)and their influencing factors,and to provide the prediction equation of vault in different periods after operation.Methods A total of 63 eyes from 32 patients who received ICL implantation to treat high myopia at the Department of Ophthalmology,Xuzhou First People’s Hospital from August to November 2020 were recruited in this study.Preoperative anterior chamber angle(ACA),anterior chamber depth(ACD),anterior chamber volume(ACV),corneal thickness(CT),white-to-white distance(WTW),sulcus-to-sulcus diameter(STS),spherical equivalent(SE),and lens thickness(LT),as well as intraoperative ICL size,were recorded,and their effect on the postoperative vault was analyzed.The vault at 1 day,1 month,6 months,and 12 months following the implantation was measured by Pentacam.Through multiple linear stepwise regression analysis,the common variables were eliminated and the independent factors were selected.With the independent factor as the independent variable and the postoperative vault as the dependent variable,the influence of said factors on the postoperative vault was analyzed.Results Patients enrolled in this study were(26.59±5.73)years old.The vault at 1 month after operation was significantly lower than that at 1 day after operation(P<0.05).The vault at 6 months after operation was significantly lower than that at 1 month after operation(P<0.05).The vault at 12 months after operation was significantly lower than that at 6 months after operation(P<0.05).Multiple linear stepwise regression analysis results showed that ACD and LT were independent factors affecting the vault after ICL implantation in patients with high myopia(both P<0.05).Spearman’s correlation analysis results showed that the postoperative vault was positively correlated with ACD,ACV and ICL size,and negatively correlated with LT(all P<0.05).The regression equations affecting the vault of patients with high myopia at 1 day,1 mon
作者
邹泉
郑洪玲
程蕾
宋超
朱冉
ZOU Quan;ZHENG Hongling;CHENG Lei;SONG Chao;ZHU Ran(Xvzhou Municipal Hospital Affiliated to Xvzhou Medical University,Xuzhou 221004,Jiangsu Province,China)
出处
《眼科新进展》
CAS
北大核心
2022年第6期456-460,共5页
Recent Advances in Ophthalmology
基金
江苏省研究生科研与实践创新计划项目(编号SJCX22-1263)。
关键词
高度近视
后房型人工晶状体
拱高
前房深度
前房容积
晶状体厚度
high myopia
implantable collamer lens
vault
anterior chamber depth
anterior chamber volume
lens thickness
