摘要
目的了解中国HBsAg阳性者对自身感染状态的知晓率及其影响因素。方法采用横断面设计,在2020年全国乙型肝炎血清流行病学调查中发现的15~69岁HBsAg阳性者中,进行自身感染状态知晓情况的问卷调查。描述总体人群及不同特征人群的知晓率,运用χ^(2)检验进行差异性比较;运用logistic回归模型分析知晓率的影响因素。结果调查对象总体知晓率为43.10%(1828/4241),其中男性知晓率低于女性(41.30%对比44.65%);60~69岁年龄段知晓率低于其他年龄段(30.38%对比36.77%~57.58%),农村地区知晓率低于城市(39.43%对比47.32%),人均地区生产总值(GDP)在5.4万元以下地区的知晓率低于5.4万元及以上地区(36.81%对比41.61%~50.30%),未合并其他肝病者的知晓率低于患有其他肝病患者(41.52%对比60.68%);无乙型肝炎相关家族史或对家族史不详者的知晓率低于有家族史者(43.58%对比68.26%;24.71%对比68.26%)。多因素logistic回归分析显示,男性[比值比(OR)=0.841,95%可信区间(CI):0.734~0.964]、高中及以下学历[小学及以下、初中、高中/中专,OR(95%CI)分别为0.247(0.190~0.321)、0.451(0.352~0.577)、0.634(0.486~0.827)]、农村地区(OR=0.822,95%CI:0.715~0.945)、人均GDP在8.0万元以下的省份[5.4万元~8.0万元,OR(95%CI):0.810(0.688~0.954);5.4万元以下,OR(95%CI):0.793(0.669~0.941)]是知晓率的负向影响因素;而30~39岁(OR=2.089,95%CI:1.626~2.683)和40~49岁(OR=1.590,95%CI:1.250~2.023)年龄组、合并其他肝病(OR=2.244,95%CI:1.754~2.871)、有乙型肝炎相关家族史(OR=2.688,95%CI:2.242~3.223)是知晓率的正向影响因素。结论中国15~69岁HBsAg阳性者对自身感染状态的总体知晓率为43.10%,应进一步加强健康宣传、扩大HBV筛查范围,以尽早达到世界卫生组织提出的2030年HBV感染诊断率达90%的目标。
Objectives To understand the awareness rate and its influencing factors of their HBV infection status among HBsAg-positive persons aged 15-69 years in China.Methods A cross-sectional design was used to conduct a questionnaire survey on the awareness of their infection status among HBsAg-positive persons aged 15-69 years who were identified in the 2020 national hepatitis B seroepidemiology survey.The awareness rate of the whole respondent and respondents with different characteristics were described,and the differences were compared with theχ^(2) test.The logistic regression model was used to analyze the factors influencing the awareness rate.Results The overall awareness rate among the respondents was 43.10%(1828/4241).The awareness rate was lower in males than in females(41.30%vs.44.65%).The awareness rate was lower in the 60-69-years-old age group than in other age groups(30.38%vs.36.77%-57.58%).The awareness rate was lower in rural areas than in urban areas(39.43%vs.47.32%).The awareness rate was lower in regions with a per capita gross domestic product(GDP)below RMB 54000 than in regions with a per capita GDP of RMB 54000 and above(36.81%vs.41.61%-50.30%).The awareness rate was lower in respondents without other liver diseases than with other liver diseases(41.52%vs.60.68%).The awareness rate was lower in respondents without a family history of hepatitis B-related disease or unknown family history than with a family history(43.58%vs.68.26%;24.71%vs.68.26%).Multivariate logistic regression analysis showed that male[odds ratio(OR)=0.841,95%confidence interval(CI):0.734-0.964],high school and below[primary school and below,junior middle school,high school/technical secondary school,OR(95%CI):0.247(0.190-0.321),0.451(0.352-0.577),0.634(0.486-0.827)],rural areas(OR=0.822,95%CI:0.715-0.945)and regions with a per capita GDP below RMB 80000[54000-80000,OR(95%CI):0.810(0.688-0.954),below RMB 54000,OR(95%CI):0.793(0.669-0.941)]were the negative factors influencing the awareness rate.While 30-39-years-old(OR=2.089,95%C
作者
孟彤彤
缪宁
郑徽
王富珍
尹遵栋
沈立萍
王宇
贾继东
孔媛媛
张国民
Meng Tongtong;Miao Ning;Zheng Hui;Wang Fuzhen;Yin Zundong;Shen Liping;Wang Yu;Jia Jidong;Kong Yuanyuan;Zhang Guomin(Department of National Immunization Program,Chinese Center for Disease Control and Prevention,Beijing 100050,China;Liver Research Center,Beijing Friendship Hospital,Capital Medical University&National Clinical Research Center for Digestive Disease,Beijing 100050,China;Clinical Epidemiology and EBM Unit,Beijing Friendship Hospital,Capital Medical University&Beijing Clinical Research Institute,Beijing 100050,China)
出处
《中华肝脏病杂志》
CSCD
北大核心
2022年第5期534-540,共7页
Chinese Journal of Hepatology
基金
国家科技重大专项(2017ZX10105015)
2022年公共卫生应急反应机制的运行-计划免疫项目(131031001000150001)
北京市科学技术委员会(Z191100007619037)。
关键词
乙型肝炎病毒
乙型肝炎表面抗原
知晓率
横断面调查
Hepatitis B virus
Hepatitis B surface antigen
Awareness rate
Cross-sectional study
