摘要
目的探究在妊娠期糖尿病合并高血压患者中应用胰岛素持续静脉滴注方法对患者的应用效果。方法选取该院2019年2月—2021年6月接收的妊娠期糖尿病合并高血压患者100例为研究对象,采用随机数字表法分为两组,每组50例。研究组应用胰岛素持续静脉滴注方法,对照组应用多次胰岛素皮下注射方法,对比观察两组患者干预后的血糖指标、血压指标、妊娠结局和新生儿结局。结果干预后,研究组患者空腹血糖(FPG)、餐后2 h血糖(2 hPG)、糖化血红蛋白(HbAlc)、收缩压和舒张压分别为(4.65±1.03)mmol/L、(6.54±1.72)mmol/L、(6.05±1.12)%、(123.24±10.77)mmHg和(83.23±11.67)mmHg,均优于对照组,差异有统计学意义(P<0.05);研究组患者剖宫产、羊水过多、产后出血、产后感染发生率和胎儿窘迫、早产儿、新生儿低血糖、新生儿窒息、新生儿黄疸发生率分别为12.00%、6.00%、4.00%、4.00%和6.00%、4.00%、4.00%、4.00%、4.00%,均优于对照组,差异有统计学意义(P<0.05)。结论在妊娠期糖尿病合并高血压患者中应用胰岛素持续静脉滴注方法,其临床效果显著,有利于改善患者血压和血糖水平,保证母婴安全,减少患者不良反应发生率,临床应用意义显著。
Objective To investigate the appliaction effect of continuous intravenous infusion of insulin on patients with gestational diabetes mellitus complicated by hypertension.Methods A total of 100 patients with gestational diabetes mellitus complicated with hypertension received in the hospital from February 2019 to June 2021 were selected as the research objects.The patients were divided into two groups by random number table method,50 cases in each group.The study group was given continuous intravenous infusion of insulin,while the control group was given multiple subcutaneous insulin injections.The blood glucose indexes,blood pressure indexes,pregnancy outcomes and neonatal outcomes were compared between the two groups after intervention.Results After the intervention,the fasting blood glucose(FPG),2 h postprandial blood glucose(2 hPG),glycosylated hemoglobin(HbAlc),systolic blood pressure and diastolic blood pressure of the patients in the study group were(4.65±1.03)mmol/L,(6.54±1.72)mmol/L,(6.05±1.12)%,(123.24±10.77)mmHg and(83.23±11.67)mmHg,respectively,all of which were better than the control group,and the difference was statistically significant(P<0.05).The incidences of cesarean section,polyhydramnios,postpartum hemorrhage,postpartum infection and the incidences of fetal distress,premature infants,neonatal hypoglycemia,neonatal asphyxia,and neonatal jaundice in the study group were 12.00%,6.00%,4.00%,4.00%and 6.00%,4.00%,4.00%,4.00%,4.00%,respectively,all were better than the control group,the difference was statistically significant(P<0.05).Conclusion The application of continuous intravenous infusion of insulin in patients with gestational diabetes mellitus and hypertension has a significant clinical effect.It is beneficial to improve the blood pressure and blood glucose levels of patients,ensure the safety of mothers and babies,and reduce the incidence of adverse reactions in patients,and has significant clinical application significance.
作者
李佳惠
陈雪琼
LI Jiahui;CHEN Xueqiong(The Second Affiliated Hospital of Fujian Medical University,Quanzhou,Fujian Province,362000 China)
出处
《糖尿病新世界》
2022年第6期11-14,共4页
Diabetes New World Magazine
关键词
胰岛素持续静脉滴注
妊娠期糖尿病
高血压
血糖控制
Continuous intravenous infusion of insulin
Gestational diabetes mellitus
Hypertension
Blood glucose control
