摘要
目的探讨免电热条件下单孔腹腔镜行卵巢子宫内膜异位囊肿剥除术对卵巢储备功能的影响。方法选取2017年1月至2020年6月该院收治的在免电热条件下微创手术行卵巢子宫异位囊肿剥除术患者120例,根据随机对照原则采用随机数字表法分为单孔组和多孔组,每组60例。比较2组患者手术情况、术后情况、手术前后卵巢储备功能(包括抗苗勒氏管激素、卵泡刺激素、促黄体生成素、雌二醇)等,并分析影响术后卵巢储备功能不足的危险因素。结果2组患者在免电热条件下手术时间、手术出血量、住院时间比较,差异均无统计学意义(P>0.05)。2组患者术后卵巢储备功能均较术前明显下降,差异均有统计学意义(P<0.05);2组患者术后发生卵巢储备功能不足率比较,差异无统计学意义(P>0.05)。年龄、手术出血量、双侧囊肿是影响术后卵巢储备功能不足的独立危险因素(优势比=0.796、0.986、0.012,95%可信区间:0.678~0.934、0.977~0.995、0.001~0.137,P=0.005、0.002、0.001)。结论免电热条件下单孔腹腔镜行卵巢子宫内膜异位囊肿剥除术是可行、安全的,术后卵巢储备功能和使用多孔腹腔镜一样可出现明显下降,年龄、手术出血量、双侧囊肿是导致卵巢储备功能不足的独立危险因素。
Objective To study the effect of ovarian endometriotic cystectomy on the ovarian reserve by laparoendoscopic single-port surgery without electrocoagulation.Methods A total of 120 patients with endometriotic cystectomy without electrocoagulation treated in our hospital from January 2017 to June 2020 were selected.According to the random control principle,the patients were randomly divided into the laparoendoscopic single-port group(single-port group,n=60)and conventional multi-port laparoscopic group(multi-port group,n=60)by the random number table method.The operation,postoperative conditions and ovarian reserve function before and after operation including anti-Müllerian hormone(AMH),follicle-stimulating hormone(FSH),luteinizing hormone(LH)and estradiol(E2)were compared between the two groups.The risk factors affecting postoperative ovarian reserve function were analyzed.Results There was no significant difference in the operation time,operative blood loss and hospital stay between the two groups(P>0.05).The ovarian reserve function of the two groups after operation was significantly lower than that before operation,and the difference was statistically significant(P<0.05).There was no significant difference in the rate of postoperative ovarian reserve deficiency between the two groups(P>0.05).The age,operative blood loss and bilateral cystectomy were the independent risk factors for the postoperative ovarian reserve deficiency(OR=0.796,0.986,0.012;95%CI:0.678-0.934,0.977-0.995,0.001-0.137;P=0.005,0.002,0.001).Conclusion The laparoendoscopic single-port surgery of ovarian endometriotic cystectomy without electrocoagulation is feasible and safe,and the ovarian reserve could be decreased significantly postoperatively as that by the conventional multi-port laparoscopy.The age,operative blood loss and the bilateral cystectomy are the independent risk factors for the postoperative ovarian reserve deficiency.
作者
黄伟容
韦利英
封意兰
赵仁峰
HUANG Weirong;WEI Liying;FENG Yilan;ZHAO Renfeng(Department of Gynecology,Guangxi Academy of Medical Science/the People′s Hospital of Guangxi Zhuang Autonomous Region,Nanning,Guangxi 530021,China)
出处
《现代医药卫生》
2022年第10期1645-1649,共5页
Journal of Modern Medicine & Health
基金
广西壮族自治区卫生健康委员会自筹科研计划课题(Z20170340)。
关键词
单孔腹腔镜
卵巢子宫内膜异位囊肿
卵巢储备功能
影响因素分析
Laparoendoscopic single-port surgery
Ovarian endometriotic cystectomy
Ovarian reserve
Analysis of influencing factors
