摘要
目的·基于大规模前瞻性社区老年人群队列,探索心脑血管疾病单患、共患人群的流行病学和危险因素特征。方法·研究的对象来源于上海社区老年人群队列。该队列的基线调查始于2019年2月,结束于2019年8月,收集了包括队列成员的人口统计学信息、疾病史和家族史、生活方式、心理状况等信息。根据自我报告有无冠状动脉性心脏病(冠心病)和/或脑卒中将全部队列成员分为4组:冠心病单患组、脑卒中单患组、心脑血管疾病(冠心病+脑卒中)共患组以及对照组(无冠心病及脑卒中)。对这4组对象的基本信息、共患其他疾病情况、生活方式、心理状况、睡眠状态等进行分析比较。结果·17948名符合入选标准的研究对象纳入队列研究,其中冠心病单患组2050名、脑卒中单患组724名、心脑血管疾病共患组269名、对照组14905名。4组人群平均年龄分别为(70.4±6.2)岁、(71.8±7.1)岁、(73.2±7.0)岁和(68.3±5.9)岁。心脑血管疾病共患组患者合并高血压(76.6%)、高脂血症(38.3%)、糖尿病(26.0%)等基础性疾病的比例最高,其次为脑卒中单患组(分别为74.2%、26.8%和25.8%)、冠心病单患组(分别为72.9%、21.1%和21.7%),而对照组最低(分别为54.6%、8.7%和15.4%)。心脑血管疾病共患组患者有抑郁症状(16.0%)、焦虑症状(13.1%)、久坐习惯(2.2%)、睡眠质量较差或很差(38.6%)的比例最高,其次是脑卒中单患组(分别为10.1%、6.6%、2.2%和27.2%)、冠心病单患组(分别为7.9%、4.8%、0.5%和27.0%)。心脑血管疾病共患组患者有规律运动习惯的比例(29.5%)最低,而对照组的规律运动比例(39.2%)最高。结论·冠心病、脑卒中患者尤其是冠心病+脑卒中共患者合并基础性疾病、具有不良生活习惯和心理疾患的比例较高。
Objective·To explore the epidemiology and risk factors of single and co-morbidity of cardio-cerebrovascular diseases based on a large-scale prospective cohort of elderly people in the community.Methods·The subjects of the study came from Shanghai Community Elderly Cohort.The baseline survey of this cohort began in February 2019 and ended in August 2019,collecting information including demographic information,diseases and family history,lifestyle and psychological status of cohort members.According to self-reported coronary heart disease and/or stroke,all cohort members were divided into four groups,which were single coronary heart disease group,single stroke group,cardio-cerebrovascular disease group(with both coronary heart disease and stroke),and control group(without coronary heart disease and stroke).Baseline information,disease history,lifestyle factors,psychological and sleep status among the four groups were analysed.Results·A total of 17948 eligible subjects participated in the cohort study,including 2050 cohort members with single coronary heart disease,724 cohort members with single stroke,269 cohort members with cardio-cerebrovascular disease,and 14905 cohort members without coronary heart disease and stroke.The average age of these four groups were(70.4±6.2)years,(71.8±7.1)years,(73.2±7.0)years and(68.3±5.9)years,respectively.The proportions of hypertension(76.6%),hyperlipidemia(38.3%)and diabetes(26.0%)were the highest in the cardiocerebrovascular disease group,followed by the single stroke group(74.2%,26.8%and 25.8%,respectively),and the single coronary heart disease group(72.9%,21.1%and 21.7%,respectively),and the control group had the lowest proportion(54.6%,8.7%and 15.4%,respectively).The proportions of depression symptoms(16.0%),anxiety symptoms(13.1%),sedentary habit(2.2%),and poor or fairly poor sleep(38.6%)in the cardio-cerebrovascular disease group were the highest,followed by the single stroke group(10.1%,6.6%,2.2%and 27.2%,respectively)and the single coronary heart disease group(7.9
作者
蒋惠如
李峥
马卓然
魏霖
袁安彩
胡刘华
陈潇雨
郭韵悦
张薇
卜军
JIANG Huiru;LI Zheng;MA Zhuoran;WEI Lin;YUAN Ancai;HU Liuhua;CHEN Xiaoyu;GUO Yunyue;ZHANG Wei;PU Jun(Department of Cardiology,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200127,China;School of Public Health,Bengbu Medical College,Bengbu 233030,China;Center for Clinical Investigation,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200127,China)
出处
《上海交通大学学报（医学版）》
CAS
CSCD
北大核心
2022年第3期282-289,共8页
Journal of Shanghai Jiao tong University:Medical Science
基金
国家重点研发计划(2018YFC1312802)
浦东新区卫生健康委员会联合攻关项目(PW2019D-11)。
