摘要
原发性骨质疏松症(POP)属“骨痿”“骨痹”“骨枯”等范畴。“骨络”是向骨组织输送营养的通路,可以将精、气、血、津液等营养物质输送至骨腔,充髓以养骨。肾中之元气,又叫元精,为人体生命的原动力,肾中精气既虚,气无以行血,血行迟滞,瘀阻骨络,则气血失职,不能濡养筋骨。因此提出“肾虚络病,瘀阻骨络”为POP发病的核心病机。骨络理论揭示了POP的确切病位,指出骨络是骨组织发挥正常功能的前提条件,使POP病位更加直观以及明确,对于治疗靶点以及选方用药都有很好的指导作用。
Primary osteoporosis(POP) belongs to the category of bone impotence, bone arthralgia, bone withered and so on. ‘Bone collaterals’ is the pathway to deliver nutrients to bone tissue, which can transport nutrients such as essence, qi, blood,liquid and fluid to bone cavity, filling the marrow and nourishing the bone. Original qi in the kidney, also known as original jing,is the driving force of human life. Kidney essence is deficiency and qi cannot promote blood, leading to blood stagnation, blood stasis block bone collaterals, then qi and blood dereliction of duty, cannot nourish bones. As a result, it is suggested that ‘kidney deficiency and collaterals disease, blood stasis and bone collaterals obstruct’ are the core pathogenesis of POP disease. Bone collateral theory reveals the exact location of POP disease and points out that the bone envelope is a prerequisite for the normal function of the bone tissue, and makes POP disease more intuitive and clearer. It provides a good guiding role for the treatment of targets and prescription drugs.
作者
王庆谚
李佳
郑洪新
WANG Qing-yan;LI Jia;ZHENG Hong-xin(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2022年第2期756-759,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家重点研发计划项目(No.2018YFC1704301)
国家自然科学基金青年科学基金项目(No.82004229)
辽宁省自然科学基金面上项目(No.2019-MS-225,No.2020-MS-222)
辽宁省自然科学基金指导计划(No.2019-ZD-0958)
辽宁省教育厅重点攻关项目(No.L202061)
辽宁省教育厅青年科技人才“育苗”项目(No.L202024)。
关键词
原发性骨质疏松症
络脉
肾
骨络
肾虚络病
瘀阻骨络
Primary osteoporosis(POP)
Collaterals
Kidney
Bone
Bone collaterals
Kidney deficiency and collaterals disease
Blood stasis and bone collaterals obstruct
