摘要
目的识别乳腺癌患者化疗期睡眠质量分类特征及生命质量差异, 为改善该群体睡眠情况与生命质量提供依据。方法采用自制一般资料调查表、匹兹堡睡眠质量指数及乳腺癌生命质量测定量表, 对2016年1—12月就诊于上海、武汉、唐山、南宁5所三级甲等医院的421例乳腺癌患者进行横断面调查。结果乳腺癌患者化疗期睡眠质量可被识别为四类:睡眠严重障碍型(C1)23例、中等入睡障碍型(C2)127例、中等睡眠过程障碍型(C3)30例与无睡眠障碍型(C4)241例, 4个潜类别人群睡眠质量总分之间差异有统计学意义(χ^(2)=309.28, P<0.05)。年龄、BMI、职业状态、手术情况、化疗疗程在不同潜类别组间差异有统计学意义(χ^(2)值为9.57~25.28, P<0.05)。C2与C3、C2与C4、C3与C1、C3与C4潜类别间在生命质量得分上差异有统计学意义(χ^(2)值为5.96~52.73, P<0.05)。结论乳腺癌患者化疗期睡眠质量存在个体异质性, 生命质量表现亦不同。医务人员应重点关注年龄大、BMI高、处于在职状态、进行了手术及化疗初期的人群, 提供针对性护理措施改善其睡眠情况与生命质量。
Objective To identify the classification characteristics and quality of life(QOL)of breast cancer(BC)patients during chemotherapy,so as to provide basis for improving the sleep and QOL of this group.Methods A cross-sectional investigation was completed among 421 BC patients in 5 tertiary hospitals in Shanghai,Wuhan,Tangshan and Nanning in 1-12 months of 2016 using validated instruments including self-made general information questionnaire,Pittsburgh Sleep Quality Index(PSQI)and Functional Assessment of Cancer Therapy-Breast(FACT-B).Results Four latent class of patients were identified through latent profile analysis(LPA),named by badly worse sleep quality(SQ)(C1,n=23),medium-SQ with difficulty to fall asleep(C2,n=127),medium-SQ with worse sleeping process(C3,n=30),none sleep disorders(C4,n=241).Total points of SQ among C1-C4 had significant difference(χ^(2) value was 309.28,P<0.05).Age,BMI,job status,whether had surgery and course of chemotherapy between classes had statistically significant differences(χ^(2) values were 9.57-25.28,all P<0.05).It had significant difference between C2 and C3,C2 and C4,C3 and C1,C3 and C4 on QOL(χ^(2) values were 5.96-52.73,all P<0.05).Conclusion SQ of BC patients during chemotherapy has heterogeneity among population.Different features of SQ of BC patients have different performance on QOL.Health professionals should keep an eye on patients with features of older age,high BMI,in job status,already received surgery and during early-stage chemotherapy,provide personal nursing intervention to improve SQ and QOL.
作者
耿朝辉
方琼
张男
沈丹薇
周立芝
孟宪静
谭虹虹
袁长蓉
Geng Zhaohui;Fang Qiong;Zhang Nan;Shen Danwei;Zhou Lizhi;Meng Xianjing;Tan Honghong;Yuan Changrong(School of Nursing,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;School of Nursing,Shanghai Jiaotong University,Shanghai 200025,China;Department of Breast Surgery,Ruijin Hospital,Shanghai Jiaotong University School of Medical,Shanghai 200025,China;Department of Breast Surgery,Tangshan People′s Hospital,Tangshan 063001,China;Department of Breast Surgery,Guangxi Medical University Affiliated Tumor Hospital,Nanning 530021,China;School of Nursing,Fudan University,Shanghai 200032,China)
出处
《中国实用护理杂志》
2022年第6期431-437,共7页
Chinese Journal of Practical Nursing
基金
国家自然科学基金(72104145、71874032)
教育部人文社会科学研究项目(21YJCZH032)
上海市"科技创新行动计划"扬帆计划(21YF1447700)。
关键词
生活质量
乳腺肿瘤
睡眠质量
潜在剖面分析
Quality of life
Breast neoplasm
Sleep quality
Latent profile analysis
