摘要
分别采用溴化丁基橡胶(BIIR)和溴化异丁烯-对甲基苯乙烯共聚物(BIMSM)为主体材料,按照适当配方制备两种硫化胶及预灌封注射器用橡胶活塞,研究高压蒸汽灭菌和γ射线辐照灭菌对BIIR和BIMSM硫化胶及活塞性能的影响。结果表明:经两种方式灭菌后,BIIR和BIMSM硫化胶都具有良好的物理性能,BIMSM硫化胶的耐高压蒸汽和耐辐照性能优于BIIR硫化胶;BIIR活塞在高压蒸汽灭菌后180 d内及在40 kGy辐照剂量γ射线辐照灭菌后零时刻的理化性能均满足YBB 00082004—2015的要求。BIMSM是制备预灌封注射器用橡胶活塞的一种更好的主体材料。
Using brominated butyl rubber(BIIR)and brominated poly(isobutylene-co-p-methylstyrene)(BIMSM)as the main materials,two kinds of vulcanizates and rubber plungers for prefilled syringe were prepared according to appropriate formulas.The Effects of high-pressure steam sterilization andγray radiation sterilization on the properties of BIIR and BIMSM vulcanizates and plungers were studied.The results showed that,BIIR and BIMSM vulcanizates both had good physical properties after sterilization by the two methods,and the high-pressure steam resistance and the radiation resistance of the BIMSM vulcanizate were better than those of the BIIR vulcanizate.Within 180 days after high-pressure steam sterilization,the physical and chemical properties of BIIR plungers met the requirements of YBB 00082004—2015.It was found that right after the 40 kGy doseγray radiation sterilization,the properties of BIIR plungers also met the requirements of YBB 00082004—2015.BIMSM was a better main material for making rubber plungers for prefilled syringe.
作者
刘海洪
崔喆
付鹏
LIU Haihong;CUI Zhe;FU Peng(Zhengzhou University,Zhengzhou 450001,China;Henan Key Laboratory of Advanced Nylon Materials and Applications,Zhengzhou 450001,China)
出处
《橡胶工业》
CAS
2022年第3期218-221,共4页
China Rubber Industry
