摘要
目的分析放射工作人员甲状腺情况及影响因素分析,为放射工作人员放射防护管理提供科学依据。方法于2020年4月,收集2017年10月1日至2019年9月30日来杭州市职业病防治院进行职业健康检查的4308名放射工作人员作为研究对象,资料包括基本信息、甲状腺激素水平、甲状腺彩超结果,比较不同亚组放射工作人员甲状腺情况,采用多因素logistic回归分析甲状腺结节的影响因素。结果调查对象中616名放射工作人员甲状腺异常(14.3%,616/4308),甲状腺异常主要表现为甲状腺结节(5.1%,220/4308)和促甲状腺激素(TSH)水平异常(7.1%,308/4308)。与男性放射工作人员比较,女性放射工作人员甲状腺结节检出率、三碘甲状腺原氨酸(T3)、TSH异常率更高(P<0.05);随着工龄增加甲状腺结节检出率、T3、甲状腺素(T4)异常率升高(P<0.05);未评级医疗机构和私营医疗机构放射工作人员甲状腺结节检出率最高(P<0.05)。经多因素logistic回归分析,女性、年龄均为甲状腺结节发生的独立危险因素(OR=2.068、1.016,95%CI:1.548~2.763、1.002~1.030,P<0.05)。结论电离辐射可引起放射工作人员甲状腺损伤,应重点关注女性、高年龄的放射工作人员放射防护管理,保障放射工作人员健康。
Objective To analyze the thyroid condition and influencing factors of radiation workers,and to provide scientific basis for radiation protection management.Methods In April 2020,4308 radiation workers from October 1,2017 to September 30,2019 were collected for occupational health examination in Hangzhou Occupational Disease Prevention and Treatment Hospital,the data included basic information,Thyroid hormone level and thyroid color doppler ultrasound results.The thyroid status of radiation workers in different subgroups was compared.The influencing factors of Thyroid nodule were analyzed by multiple logistic regression.Results 616 radiation workers had abnormal thyroid gland(14.3%,616/4308).The main manifestations of thyroid gland abnormality were abnormal Thyroid nodule(5.1%,220/4308)and abnormal TSH level(7.1%,308/4308).Compared with the male radiation workers,the abnormal rate of Thyroid nodule,T3 and Tsh in female radiation workers was higher(P<0.05),and the abnormal rate of Thyroid nodule,T3 and T4 increased with the increase of working age(P<0.05).Radiation Workers in non-rated medical institutions and private medical institutions had the highest detection rate of Thyroid nodule(P<0.05),and there was no significant difference in thyroid abnormalities among Workers(P<0.05).By multiple logistic regression analysis,Sex(female),age and institution type(private)were all independent risk factors for Thyroid nodule(95%CI:1.548~2.763、1.002~1.030,P<0.05).Conclusion Ionizing radiation can cause thyroid damage in radiation workers,so we should pay more attention to the radiation protection management of female,high age,private and district medical organizations,so as to protect the health of radiation workers.
作者
杨勇
王强
杨陆婷
赵徵鑫
Yang Yong;Wang Qiang;Yang Luting;Zhao Zhixin(Hangzhou Hospital for Prevention and Treatment of Occupational Diseases,Hangzhou 310014,China)
出处
《中华劳动卫生职业病杂志》
CAS
CSCD
北大核心
2022年第2期113-116,共4页
Chinese Journal of Industrial Hygiene and Occupational Diseases
基金
杭州市科技计划引导项目(20191231Y055)
杭州市医药卫生科技项目(A20200566,A20200795)
浙江省卫生健康科技计划(2021KY956)。
关键词
放射学
促甲状腺激素
甲状腺激素
甲状腺结节
流行病学
影响因素
Radiology
Thyrotropin,Thyroid stimulating hormone
Thyroid hormones
Thyroid nodules
Epidemiology
Influence factor