摘要
缺血性卒中是目前中国人口死亡的主要原因之一。除高血压病、糖尿病、吸烟等常见的高危因素外,卵圆孔未闭(PFO)及阻塞性睡眠呼吸暂停综合征(OSAS)也是其独立危险因素,且PFO在OSAS患者中的检出率较高,二者常常共病。二者共病时可能通过加重反常性栓塞的风险使缺血性卒中患病率及复发率增高。作者就PFO合并OSAS可能增加反常性栓塞风险引发缺血性卒中的研究进展进行了综述。
Ischemic stroke is one of the main causes of death in the Chinese population.In addition to common factors such as hypertension,diabetes,and smoking,patent foramen ovale(PFO)and obstructive sleep apnea syndrome(OSAS)are also independent risk factors for ischemic stroke.The detection rate of PFO in patients with OSAS is high,and they are often comorbid.When the two are comorbid,the incidence and recurrence rate of stroke may be significantly higher by aggravating the risk of paradoxical embolism.This article reviews the research progress on concurrence of PFO and OSAS with increased risk of ischemic stroke caused by paradoxical embolism.
作者
孙永飞
周彤
罗勇
詹剑
Sun Yongfei;Zhou Tong;Luo Yong;Zhan Jian(Department of Neurology,the Second Affiliated Hospital of Zunyi Medical University,Zunyi,Guizhou 563000,China)
出处
《中国脑血管病杂志》
CAS
CSCD
北大核心
2022年第3期205-210,共6页
Chinese Journal of Cerebrovascular Diseases
基金
贵州省卫生健康委科学技术基金项目(gzwjkj2019-1-060)。