摘要
目的探讨白细胞计数(WBC)、C反应蛋白(CRP)和降钙素原(PCT)在恶性疟疾诊断中的应用价值。方法选取非洲加蓬共和国弗朗斯维尔市中加友谊医院2020年9月至2021年6月收治的各型疟疾患者60例[恶性疟疾组45例,其他型疟疾(间日疟、三日疟和卵型疟)组15例],并选取该医院同期的健康查体者21名作为对照组,比较3组的WBC、CRP和PCT水平,并分析WBC、CRP和PCT诊断恶性疟疾的效能。结果恶性疟疾组的WBC、CRP和PCT水平均高于其他型疟疾组和对照组,差异有统计学意义(P<0.05);CRP和PCT诊断恶性疟疾的灵敏度高于WBC,差异有统计学意义(P<0.05)。结论WBC、CRP和PCT对恶性疟疾有一定的诊断价值,CRP和PCT可作为病情评估及预后判定的参考指标。
Objective The application value of white blood cell count(WBC),C reactive protein(CRP)and procalcitonin(PCT)in the diagnosis of falciparun malaria was explored.Methods 60 cases of malaria patients covering various kinds admitted to China-Gabon Friendship Hospital of Franceville in Gabon from September 2020 to July 2021 were selected as the research objects.They were divided into two groups:the falciparum malaria group(45 cases)and the other malaria group(15 cases)covering plasmodium vivax,plasmodium malariae and plasmodium ovale.21 health checkers admitted to the hospital during the same period were selected as the control group.The levels of WBC,CRP and PCT in the three group were compared and the efficacy of WBC,CRP and PCT in diagnosing falciparum malaria was analyzed.Results The levels of WBC,CRP and PCT in the falciparum malaria group were higher than those in the other malaria group and the control group,with statistically significant difference(P<0.05);The sensitivity and specificity of PCT and CRP in the diagnosis of falciparum malaria were higher than WBC,with statistically significant differences(P<0.05).Conclusion WBC,CRP and PCT are helpful in the diagnosis of falciparum malaria,PCT and CRP can be used as reference indexes for disease assessment and prognosis judgment.
作者
李世佳
Charline Nganianga
Li Shijia;Charline Nganianga(Clinical Laboratory,Tianjin Forth Central Hospital,Tianjin 300143,China;Clinical Laboratory,China-Gabon Friendship Hospital of Franceville in Gabon,Franceville 3725,Gabon)
出处
《医疗装备》
2022年第3期49-51,共3页
Medical Equipment
关键词
恶性疟疾
白细胞计数
C反应蛋白
降钙素原
加蓬
Falciparum malaria
White blood cell count
C reactive protein
Procalcitonin
Gabon
