摘要
目的 优化液相色谱串联质谱测定塑料制品中双酚F和双酚S迁移量的方法。方法 通过色谱条件及质谱条件的优化,迁移实验所得食品模拟物经C18柱分离、甲醇-氨水洗脱、多反应模式监测、外标法定量。结果 优化条件下,双酚F和双酚S线性关系良好,水基模拟物的检出限为4μg/L和0.2μg/L、定量限为10μg/L和0.5μg/L,油基模拟物的检出限为20μg/kg和1μg/kg、定量限为50μg/kg和2.5μg/kg,回收率为89.2%~105.5%,RSD值为1.42%~6.18%。结论 该法准确、灵敏,适用于食品包装塑料双酚F和双酚S迁移量的测定。
The work aims to optimize the method of determining migration of bisphenol F and bisphenol S in food packaging plastics by HPLC-MS/MS. Under the optimized conditions of chromatography and mass spectrometry, the food simulants obtained from migration test were separated by C18 column, eluted by methanol-ammonia, monitored by multiple-reaction monitoring mode and quantified by external standard method. The linear relationship of bisphenol F and bisphenol S was good. The detection limits of water-based simulant were 4 μg/L and 0.2 μg/L, and quantitative limits were 10 μg/L and 0.5 μg/L, while the detection limits of oil-based were 20 μg/kg and 1 μg/kg and quantitative limits were 50 μg/kg and 2.5 μg/kg. The recovery rate was 89.2%~105.5% and RSD was 1.42%~6.18%. The method is accurate and sensitive, and suitable for the migration determination of bisphenol F and bisphenol S in food packaging plastics.
作者
陈旭明
李婷
徐思飞
CHEN Xu-ming;LI Ting;XU Si-fei(China National Quality Supervision and Testing Center for Food Flexible Packaging Product and Machinery(Guangdong),Chaozhou 521011,China)
出处
《包装工程》
CAS
北大核心
2022年第5期115-121,共7页
Packaging Engineering
基金
潮州市科学技术局科研项目(2019GY08)。
关键词
食品包装
塑料
双酚F和双酚S
迁移量
优化
分析
food packaging
plastics
bisphenol F and bisphenol S
migration
optimization and analysis
