摘要
目的:分析难治性肺炎患儿支气管肺泡灌洗液标本细菌培养及耐药性。方法:选取河南省中医药研究院附属医院2017年3月至2019年9月收治的难治性肺炎患儿115例,取支气管肺泡灌洗液标本进行细菌培养,分析抗菌药物耐药性。结果:115例难治性肺炎患儿支气管肺泡灌洗液标本共培养出病原菌81株,其中革兰阳性菌30株(37.04 %),革兰阴性菌47株(58.02 %),真菌4株(4.94 %);肺炎链球菌对四环素、红霉素等耐药性较高,金黄色葡萄球菌对青霉素、阿莫西林等耐药性较高,肺炎克雷伯菌对氨苄西林、头孢唑林、头孢曲松等耐药性较高。结论:难治性肺炎患儿支气管肺泡灌洗液标本细菌培养中肺炎链球菌、肺炎克雷伯菌等较常见,应依照细菌培养结果、耐药性分析结果进行临床治疗。
Objective To analyze the bacterial culture and drug resistance of bronchoalveolar lavage fluid in children with refractory pneumonia.Methods A total of 115 children with refractory pneumonia admitted to the Affiliated Hospital of Henan Academy of Traditional Chinese Medicine from March 2017 to September 2019 were selected.Bronchoalveolar lavage fluid samples were collected for bacterial culture to analyze antimicrobial resistance.Results 81 strains of pathogenic bacteria were cultured in bronchoalveolar irrigation fluid of 115 children with refractory pneumonia,including 30 strains of gram-positive bacteria (37.4%),47 strains of gram-negative bacteria (58.2%) and 4 strains of fungi (4.94%).Streptococcus pneumoniae has high resistance to tetracycline and erythromycin,staphylococcus aureus has high resistance to penicillin and amoxicillin,and Klebsiella pneumoniae has high resistance to ampicillin,cefazolin and ceftriaxone.Conclusion Streptococcus pneumoniae and Klebsiella pneumoniae are more common in the culture of bronchoalveolar lavage fluid in children with refractory pneumonia,and clinical treatment should be conducted according to the results of bacterial culture and drug resistance analysis.
作者
陈恋恋
李芳
CHEN Lian-Lian;LI Fang(The Affiliated Hospital of Henan Academy of Traditional Chinese Medicine,Henan Zhengzhou 450000)
出处
《深圳中西医结合杂志》
2021年第20期115-117,共3页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
关键词
难治性肺炎
支气管肺泡灌洗液标本
细菌培养
耐药性
儿童
Refractory pneumonia
Bronchoalveolar lavage fluid specimens
Bacterial culture
Drug resistance
Children
