摘要
背景急性病患者常自我用药,易导致药物不良事件的发生率大幅增加。新医改多重政策实施背景下,针对急性病患者家庭用药合理性和药品可及性的调查研究较少,且已有的调查研究多集中于中、东部地区。目的了解甘肃省急性病患者家庭用药合理性和药品可及性现况,为规范甘肃省急性病患者家庭用药行为,提高其用药合理性和药品可及性提供参考依据。方法依据世界卫生组织(WHO)《药品可及性及药品使用情况入户调查指南》,拟定调查问卷。采取分层多阶段随机整群抽样法,于2018年6—12月选取甘肃省5市共1080户家庭作为调查户,采用自设问卷对过去2周家庭成员患急性病情况、因患急性病服药情况及相关药品可及性状况等进行调查,并对调查结果进行分析。采用Spearman秩相关分析急性病患者患急性病情况、药品地理可及性、药品可获得性与其服用药品、抗菌药物数量间的相关性。结果共发放问卷1080份,回收有效问卷1071份,有效问卷回收率为99.17%。调查结果显示,389户(36.32%)家庭过去两周有急性病患者。本研究选取每户中年龄最小的急性病患者进行调查,共纳入急性病患者389例。其中350例(89.97%)患急性上呼吸道感染,355例(91.26%)因患急性病产生就诊或购药行为,355例(91.26%)因患急性病服药。因患急性病服药的调查对象中,279例(78.59%)存在联合用药,93例(26.20%)同时服用≥4种药品,151例(42.54%)服用了抗菌药物。151例因急性病共使用168例次抗菌药物,其中133例次(79.17%)来自医生推荐,136例次(80.95%)为β-内酰胺类药物。药品可及性方面,334例(85.86%)急性病患者15 min以内能够到达最近的医疗服务机构;分别有354例(91.00%)、329例(84.58%)急性病患者认为其所需药品能在公立医疗机构、药店购得。355例因患急性病服药的调查对象中,349例(98.31%)有医保,其中仅有64例(18.34%)急性病药品�
Background Self-medication behavior often occurs in acutely ill patients,which may lead to a greatly increased risk of adverse drug events.There are few surveys on the accessibility and rationality of in-home self-medication among acute disease patients against a background of implementing multiple policies associated with China's healthcare reform initiated in 2009,and the available surveys mainly focus on central and eastern China.Objective To investigate the accessibility and rationality of in-home self-medication among acute disease patients in Gansu,offering evidence for standardizing in-home medication,and improving accessibility and rationality of in-home self-medication in this group.Methods By use of multistage stratified random sampling,1080 households were selected from five cities in Gansu Province from June to December 2018.They were invited to attend a survey guided by the WHO Household Survey to Measure Access to and Use of Medicines for understanding the morbidity in household members in the past two weeks,use and accessibility of medicines for treating acute diseases using a questionnaire developed by our research team.The survey results were statistically analyzed.Spearman correlation analysis was used to analyze the correlation between acute diseases,accessibility and availability of medicines for treating acute diseases and the number of drugs and antibiotics.Results Out of the 1080 households,1071(99.17%)effectively responded to the survey.The prevalence of acute diseases in family members living in these households in the past two weeks was 36.32%(389/1071).In this study,we only included the youngest family member with acutely disease in each household,that is,389 cases in all.Of them,350(89.97%)had an acute upper respiratory infection;355(91.26%)had the behavior of seeing a doctor or buying drugs;355(91.26%)were on medication for treating acute diseases.Among all cases on medication,279(78.59%)used combination therapy,93(26.20%)had four or more medications simultaneously,and 151(42.54%)were
作者
曹瑾
张铭
赵俊贤
赵帅翔
吕萌
赵思雅
胡明
王晓辉
CAO Jin;ZHANG Ming;ZHAO Junxian;ZHAO Shuaixiang;LYU Meng;ZHAO Siya;HU Ming;WANG Xiaohui(School of Public Health,Lanzhou University,Lanzhou 730000,China;National Clinical Research Center for Child Health and Disorders/Children's Hospital of Chongqing Medical University,Chongqing 400014,China;West China School of Pharmacy,Sichuan University,Chengdu 610041,China)
出处
《中国全科医学》
CAS
北大核心
2022年第4期438-444,452,共8页
Chinese General Practice
基金
国家自然科学基金资助项目(71473170)。
关键词
急性病
家庭用药
合理性
可及性
甘肃
Acute disease
Family medication
Rationality
Accessibility
Gansu
