摘要
目的探讨AngioJet机械吸栓术与导管接触性溶栓术(CDT)治疗急性下肢动脉栓塞的临床疗效。方法收集2018年1月至2020年1月佳木斯大学附属第一医院收治的64例急性下肢动脉栓塞患者的临床资料,根据治疗方式的不同将患者分为AngioJet组(接受AngioJet机械吸栓术治疗,n=34)和CDT组(接受CDT治疗,n=30)。比较两组患者的术后通畅情况,包括术后即时通畅率、术后1个月通畅率、术后6个月通畅率、术后并发症发生情况、住院时间、住院费用及总尿激酶用量。结果两组患者的术后即时通畅率、术后1个月通畅率、术后6个月通畅率比较,差异均无统计学意义(P>0.05)。AngioJet组患者的并发症总发生率为5.9%(2/34),低于CDT组患者的26.7%(8/30),差异有统计学意义(P<0.05)。AngioJet组患者的住院时间明显短于CDT组患者,住院费用明显高于CDT组患者,总尿激酶用量明显少于CDT组患者,差异有统计学意义(P<0.01)。结论AngioJet机械吸栓术与CDT治疗急性下肢动脉栓塞均具有较好的临床疗效,但AngioJet机械吸栓术的安全性更高,尿激酶用量更少,术后住院时间更短,术后总并发症发生率更低。
Objective To investigate the clinical efficacy of the AngioJet mechanical thrombectomy and catheter-directed thrombolysis(CDT)in the treatment of acute lower extremity arterial embolism.Method The clinical data of 64 patients with acute lower extremity arterial embolism admitted to the First Affiliated Hospital of Jiamusi University from January 2018 to January 2020 were collected.And the patients were divided into the AngioJet group(receiving AngioJet mechanical aspiration treatment,n=34)and the CDT group(receiving CDT treatment,n=30)according to different treatment methods.The postoperative patency of the two groups was compared,and the other reference indicators included immediate postoperative patency rate,one-month postoperative patency rate,six-month postoperative patency rate,postoperative complications,hospitalization time,hospitalization expenses,and total urokinase dosage consumption.Result There was no significant difference in the immediate postoperative patency rate,one-month postoperative patency rate,and six-month postoperative patency rate between the two groups(P>0.05).The total incidence of complications in the AngioJet group was 5.9%(2/34),which was lower than 26.7%(8/30)in the CDT group,and the difference was statistically significant(P<0.05).The hospitalization time of the AngioJet group was significantly shorter than that of the CDT group,and the hospitalization expenses was significantly higher than that of the CDT group,and the total urokinase consumption was significantly less than that of the CDT group,the differences were statistically significant(P<0.01).Conclusion AngioJet mechanical thrombectomy system could achieve a good clinical effect in the treatment of acute lower extremity arterial embolism as CDT.Of note,the AngioJet thrombectomy system is safer with less urokinase,shorter postoperative hospital stay,and lower risk of postoperative complications compared with the traditional interventions.
作者
战明威
王瀚锐
杨婷
金松
Zhan Mingwei;Wang Hanrui;Yang Ting;Jin Song(Department of Vascular Surgery,the First Affiliated Hospital of Jiamusi University,Jiamusi 154000,Heilongjiang,China)
出处
《血管与腔内血管外科杂志》
2021年第9期1069-1073,共5页
Journal of Vascular and Endovascular Surgery
