摘要
【目的】观察知柏地黄汤合八正散加减治疗尿路感染(淋证)阴虚湿热证的临床疗效。【方法】将84例尿路感染(淋证)阴虚湿热证患者随机分为治疗组和对照组,每组各42例。对照组给予尿感宁颗粒治疗,治疗组给予知柏地黄汤合八正散加减治疗,连续治疗2周。观察2组患者治疗前后尿白细胞数和中医证候积分的变化情况,评价2组患者的中医证候疗效和西医临床疗效。【结果】(1)中医证候疗效方面:治疗2周后,治疗组的总有效率为92.86%(39/42),对照组为78.57%(33/42),组间比较,治疗组的中医证候疗效明显优于对照组(P<0.01)。(2)西医临床疗效方面:治疗2周后,治疗组的总有效率为90.48%(38/42),对照组为80.95%(34/42),组间比较,治疗组的西医临床疗效明显优于对照组(P<0.01)。(3)治疗后,2组患者的中医证候积分和尿白细胞数均较治疗前明显降低(P<0.05),且治疗组对中医证候积分和尿白细胞数的降低作用均明显优于对照组(P<0.05)。【结论】知柏地黄汤合八正散加减治疗尿路感染(淋证)阴虚湿热证患者疗效确切,其疗效优于中成药尿感宁颗粒。
Objective To observe the clinical efficacy of modified Zhi Bo Dihuang Decoction plus Bazheng Powder in the treatment of yin deficiency and damp-heat type of urinary tract infection. Methods Eighty-four cases of urinary tract infection(stranguria)with yin deficiency and damp-heat syndrome were randomly divided into treatment group and control group, 42 cases in each group. The control group was treated with Niaoganning Granules,and the treatment group was treated with modified Zhi Bo Dihuang Decoction and Bazheng Powder for2 consecutive weeks. The changes of urinary white blood cell(U-WBC)count and traditional Chinese medicine(TCM)syndrome scores in the two groups before and after treatment were observed, and the TCM syndrome efficacy and western medicine efficacy in the two groups were evaluated. Results(1)TCM syndrome efficacy:after 2 weeks of treatment,the total effective rate of the treatment group was 92.86%(39/42),and that of the control group was 78.57%(33/42). The intergroup comparison showed that the TCM syndrome efficacy of the treatment group was significantly superior to that of the control group(P < 0.01).(2)Western medicine efficacy:after 2 weeks of treatment,the total effective rate of the treatment group was 90.48%(38/42),and that of the control group was 80.95%(34/42). The intergroup comparison showed that the western medicine efficacy in the treatment group was significantly superior to that in the control group(P < 0.01).(3)After treatment,the TCM syndrome scores and the urinary white blood cell count of the two groups were significantly decreased compared with those before treatment(P < 0.05),and the effect on decreasing the TCM syndrome scores and the urinary white blood cell count in the treatment group was superior to that in the control group(P < 0.05). Conclusion Modified Zhi Bo Dihuang Decoction plus Bazheng Powder exerts certain effect in treating patients with yin deficiency and damp-heat type of urinary tract infection,and its curative effect is superior to that of Chinese patent medic
作者
严安琪
赵冬
YAN An-Qi;ZHAO Dong(The Fifth Clinical Medical School of Guangzhou University of Chinese Medicine,Guangzhou 510405 Guangdong,China;Guangdong Second Traditional Chinese Medicine Hospital,Guangzhou 510095 Guangdong,China)
出处
《广州中医药大学学报》
CAS
2021年第12期2598-2602,共5页
Journal of Guangzhou University of Traditional Chinese Medicine
关键词
知柏地黄汤
八正散
尿感宁颗粒
尿路感染
淋证
阴虚湿热证
Zhi Bo Dihuang Decoction
Bazheng Powder
Niaoganning Granules
urinary tract infection
stranguria
yin deficiency and damp-heat syndrome
