摘要
目的了解近40年痰瘀互结相关研究热点演变情况,分析痰瘀互结研究方向与趋势。方法计算机检索中国知识资源总库(CNKI)、中文科技期刊数据库(维普网)、中国学术期刊数据库(万方数据)、PubMed、Embase建库至2021年3月1日收录的痰瘀互结相关研究文献。采用EndNote X8、Visual Studio Code软件进行文献筛查、管理。采用Excel2010对文献信息进行整理归类,建立数据库。采用SPSS22.0统计软件进行数据分析,采用VOSviewer软件进行可视化展示。统计得出重点研究的疾病病种、研究目的、研究方法等,并分析其热度演变情况,在此基础上判断未来研究趋势。结果纳入痰瘀互结相关文献3063篇,按1982-2000年、2001-2010年、2011-2021年分为3个时间段。近40年来该领域研究均以慢性非传染性疾病热度最高,其中以心血管疾病和代谢性疾病为主,冠心病最多见,高血压、脂肪性肝病次之。1990-2000年以总结热点疾病的治疗经验为主,之后2个时间段多针对热点疾病开展临床研究以提供疗效证据。此外,分析痰瘀互结证与理化指标的相关性研究在3个时间段呈持续上升趋势,近10年逐渐兴起痰瘀互结客观化、量化的标准研究。通过痰瘀互结相关研究热点演变分析提出研究发展趋势:第一,痰瘀互结证临床诊治逐渐规范化;第二,支撑从痰瘀互结论治重大疾病的高质量临床研究证据越来越多;第三,痰瘀互结证生物学基础研究向多组学整合分析方向发展。结论近40年痰瘀互结相关研究主要围绕心血管及代谢性疾病的诊治,重点开展临床研究以提供高质量证据,临床诊治逐步规范化;随着微观层面研究的深入,痰瘀互结的生物学基础将得到进一步揭示。
Objective To understand evolution of related research hotspots of phlegm and stasis interaction in the recent 40 years;To analyze the direction and trend of studies on phlegm and stasis interaction.Methods Related literature about phlegm and stasis interaction from CNKI,VIP,Wanfang Data,PubMed and Embase from establishment to 1^(st) of March 2021 was searched.EndNote X8 and Visual Studio Code software were used for document screening and management.Excel2010 was used to sort the literature information and build a database.SPSS22.0 statistical software was used for analysis,and VOSviewer software was used for visual display.The key research diseases,research purposes,research methods,etc.,were obtained and the evolution of the hotspots was analyzed.Future research trends were determined on this basis.Results A total of 3063 articles related to phlegm and stasis interaction were included,which were divided into 3 time periods according to 1982-2000,2001-2010,and 2011-2021.In the past 40 years,studies in this field have focused on chronic non-communicable diseases,with cardiovascular diseases and metabolic diseases as the main ones,coronary heart disease the most common,hypertension and fatty liver disease second.From 1990 to 2000,the main focus was to summarize the treatment experience of hotspot diseases,and then clinical studies were carried out for hotspot diseases to provide evidence of efficacy in the following two time periods.In addition,the analysis of the correlation between phlegm and stasis interaction syndrome and physical and chemical indicators showed a continuous upward trend in the three time periods.In recent 10 years,the objective and quantitative standard research of phlegm and stasis interaction syndrome has gradually emerged.According to the evolution analysis of research hotspots related to phlegm and stasis interaction,the research development trend was proposed:first,the clinical diagnosis and treatment of phlegm and stasis interaction were gradually standardized;second,there was more and mo
作者
吴珊
王传池
张佳乐
胡镜清
WU Shan;WANG Chuanchi;ZHANG Jiale;HU Jingqing(Institute of Basic Theory for Chinese Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China)
出处
《中国中医药信息杂志》
CAS
CSCD
2022年第1期11-18,共8页
Chinese Journal of Information on Traditional Chinese Medicine
基金
国家重点研发计划(2019YFC1708501)
国家重点基础研究发展计划(2014CB542903)
中央级公益性科研院所基本科研业务费专项资金(YZ-202051)。
关键词
痰瘀互结
研究热点
热点演变
趋势
VOSviewer
可视化
phlegm and stasis interaction
research hotspots
hotspots evolution
trend
VOSviewer
visualization
