摘要
目的分析彩超对2型糖尿病周围血管病变患者的临床诊断价值,以及此类患者血清25(OH)D_(3)、空腹C肽和生长抑素水平。方法选取2019年1月12日—2020年11月10日在沈阳急救中心进行诊治的60例2型糖尿病周围血管病变患者作为病变组,另选取同期收治的60例单纯2型糖尿病无周围血管病变患者作为无病变组,同时选取同期60例健康志愿者作为对照组。比较三组受试者血管彩超检查指标,以及血清25(OH)D_(3)、空腹C肽和生长抑素水平。以数字减影血管检查结果为金标准,分析彩超诊断2型糖尿病周围血管病变的效能。结果病变组脉搏波传导速度、踝肱指数及脉压指数均高于无病变组及对照组,而踝臂指数低于无病变组及对照组,差异均有统计学意义(P值均<0.05)。以数字减影血管检查为金标准,彩超诊断2型糖尿病周围血管病变的灵敏度、特异度及准确度分别为73.33%、75.00%及74.17%。病变组血清25(OH)D_(3)、空腹C肽和生长抑素水平均低于无病变组及对照组,差异均有统计学意义(P值均<0.05)。结论彩超对2型糖尿病周围血管病变具有较好的临床诊断效能,而且,2型糖尿病周围血管病变患者的血清25(OH)D_(3)、空腹C肽和生长抑素水平降低,此3项指标可能对该病具有一定的辅助诊断价值。
Objective To analyze the clinical diagnostic value of color Doppler ultrasound in patients with type 2 diabetes peripheral vascular disease,and the levels of serum 25(OH)D_(3),fasting C peptide and somatostatin in such patients.Methods A total of 60 patients with type 2 diabetes peripheral vascular disease who were diagnosed and treated in Shenyang Emergency Center from January 12th,2019 to November 10th,2020 were selected as the lesion group.The other 60 patients with simple type 2 diabetes without peripheral vascular disease were selected as the non-lesion group.Meanwhile,a total of 60 healthy volunteers were selected as the control group.The vascular color Doppler ultrasound indexes,serum 25(OH)D_(3),fasting C-peptide and somatostatin levels were compared among the three groups.Using digital subtraction angiography as the gold standard,the effectiveness of color Doppler ultrasound in diagnosing peripheral vascular disease of type 2 diabetes is analyzed.Results The pulse wave velocity,ankle brachial index and pulse pressure index in the lesion group were significantly higher than those in the non-lesion group and the control group,while the ankle brachial index was significantly lower than those in the non-lesion group and the control group(P<0.05).With the digital subtraction angiography as the gold standard,the sensitivity,specificity and accuracy of color Doppler ultrasound in diagnosing peripheral vascular disease of type 2 diabetes were 73.33%,75%and 74.17%respectively.The levels of serum 25(OH)D_(3),fasting C-peptide and somatostatin in the lesion group were significantly lower than those in the non-lesion group and the control group(P<0.05).Conclusion Color Doppler ultrasound has a good clinical diagnostic effect for peripheral vascular disease of type 2 diabetes,and the serum levels of 25(OH)D_(3),fasting C peptide and somatostatin in patients with type 2 diabetes peripheral vascular disease are decreased.These three indicators may have certain diagnostic value for this disease.
作者
霍光
HUO Guang(Color Ultrasound Room,Shenyang Emergency Center,Shenyang 110006,Liaoning Province,China)
出处
《中国实用乡村医生杂志》
2021年第11期49-52,共4页
Chinese Practical Journal of Rural Doctor
关键词
2型糖尿病
并发症
周围血管病变
诊断
彩超
效能
25(OH)D_(3)
空腹C肽
空腹生长抑素
Type 2 Diabetes Mellitus
Complication
Peripheral Vascular Disease
Diagnosis
Color Doppler Ultrasound
Effect
25(OH)D_(3)
Fasting C Peptide
Fasting Somatostatin
