摘要
目的:探究中西医结合治疗小儿哮喘的有效性及对血清炎性因子水平的影响。方法:选取2019年3月-2020年6月本院收治的哮喘患儿96例,将患儿随机分为两组,每组48例。对照组接受布地奈德联合孟鲁司特治疗,研究组在对照组基础上加入中药治疗。比较两组的临床指标效果、血气分析指标、肺功能指标以及炎性因子水平。结果:研究组的临床治疗效果明显优于对照组,差异有统计学意义(P<0.05)。治疗前,两组FVC、FEV_(1)、FEV1/FVC%比较,差异均无统计学意义(P>0.05);治疗后,研究组的肺部功能指标均明显优于对照组,差异均有统计学意义(P<0.05)。治疗前,两组pH值、PaO_(2)、PaCO_(2)比较,差异均无统计学意义(P>0.05);治疗后,研究组pH值、PaO_(2)、PaCO_(2)均优于对照组,差异均有统计学意义(P<0.05)。治疗前,两组hs-CRP、IL-6、TNF-α水平比较,差异均无统计学意义(P>0.05);治疗后,研究组上述炎性因子水平均明显低于对照组,差异均有统计学意义(P<0.05)。结论:应用中西医结合治疗小儿哮喘可以有效改善患者的肺部功能,持续降低炎性因子水平,优化血气分析指标,促使临床治疗效果趋于理想化,值得推广应用。
Objective:To explore the effectiveness of integrated traditional Chinese and Western medicine in the treatment of children asthma and its influence on the level of serum inflammatory factors.Method:A total of 96 children with asthma admitted to our hospital from March 2019 to June 2020 were selected and randomly divided into two groups,48 children in each group.The control group received Budesonide combined with Montelukast treatment,the research group added traditional Chinese medicine treatment on the basis of the control group.The clinical effects,blood gas analysis indexes,lung function indexes and inflammatory factors levels of the two groups were compared.Result:The clinical treatment effect of the study group was significantly better than that of the control group,the difference was statistically significant (P<0.05).Before treatment,there were no significant differences in FVC,FEV;and FEV_(1)/FVC% between two groups (P>0.05);after treatment,the pulmonary function indexes of the study group were significantly better than those of the control group,the differences were statistically significant (P<0.05).Before treatment,there were no significant differences in pH,PaO_(2) and PaCO_(2) between the two groups (P>0.05);after treatment,the pH value,PaO_(2) and PaCO_(2) of the study group were better than those of the control group,the differences were statistically significant (P<0.05).Before treatment,there were no significant differences in hs-CRP,IL-6 and TNF-α levels between two groups (P>0.05);after treatment,the levels of these inflammatory factors in the study group were significantly lower than those in the control group,the differences were statistically significant (P<0.05).Conclusion:The application of integrated traditional Chinese and western medicine in the treatment of infantile asthma can effectively improve the lung function of patients,continue to reduce the level of inflammatory factors,optimize the blood gas analysis index,promote the clinical treatment effect tends to be ideal,worthy of pop
作者
郭锦华
GUO Jinhua(Jiamusi Maternal and Child Health Hospital,Jiamusi 154002,China)
出处
《中国医学创新》
CAS
2021年第30期95-99,共5页
Medical Innovation of China
关键词
布地奈德
孟鲁司特
六君子汤
小儿哮喘
有效性
炎性因子
血气分析指标
Budesonide
Montelukast
Liujunzi Decoction
Pediatric asthma
Effectiveness
Inflammatory factor
Blood gas analysis indexes
