摘要
妇科肿瘤是临床多发病,严重威胁患者的健康安全。常规给予手术、放疗、化疗治疗,但是术后并发症多,复发率高,远期疗效不理想。光动力学疗法(PDT)是一种新型治疗癌症的方法,尤其是随着激光技术和激光医学的不断发展,光动力学疗法趋于成熟和稳定。该疗法的发展为妇科肿瘤治疗提供了新的方向,但是在妇科肿瘤治疗中躯体的有效性、安全性仍然尚未完全明确。本文以下对光动力学疗法作用机制以及在癌前病变、宫颈癌、卵巢癌、子宫内膜癌中的应用进展进行综述,以期为妇科肿瘤的治疗提供一定的参考依据。
Gynecological tumor is a kind of frequently-occurring disease in clinic,which threatens the health and safety of patients seriously.Surgery,radiotherapy and chemotherapy are given routinely,but there have many postoperative complications,high recurrence rate and poor long-term effect.Photodynamic therapy(PDT)is a new method to treat cancer,especially with the development of laser technology and laser medicine,PDT tends to be mature and stable.The development of PDT provides a new direction for the treatment of gynecological tumors,but the efficacy and safety of PDT in the treatment of gynecological tumors are still not clear.In this paper,the mechanism of photodynamic therapy and its application in cervical intraepithelial lesions,cervical cancer,ovarian cancer and endometrial cancer are reviewed,in order to provide some references for the treatment of gynecological tumors.
作者
李宏
LI Hong(Department of Gynecology,Tianjin Fifth Central Hospital,Tianjin 300450,China)
出处
《医学信息》
2021年第21期49-51,共3页
Journal of Medical Information
关键词
光动力学疗法
妇科肿瘤
光敏剂
Photodynamic therapy
Gynecological tumors
Photosensitizer
