摘要
乙型肝炎病毒(hepatitis B virus,HBV)是严重危害人类健康的具有传染性的病毒之一,全世界慢性HBV感染者超过2.57亿人,每年约有88.7万人死于慢性HBV感染所致的肝硬化合并症、肝衰竭及原发性肝细胞癌,给社会及个体均造成了严重伤害。在我国,慢乙肝最主要的传播途径是母婴传播(mother-to-child transmission,MTCT)。因此,阻断HBV的MTCT是预防乙型肝炎发生发展的重要措施。本文拟对目前国内外有关阻断HBV MTCT的相关研究进行综述,希望能够对临床实践提供帮助。
Hepatitis B virus(HBV)is one of the infectious viruses that seriously endanger human health.There are more than 257 million people infected with chronic HBV in the world,and about and about 887 thousand people die of cirrhosis,liver failure and hepatocellular carcinoma caused by chronic HBV infection every year.It has caused serious harm to society and individuals.In China,the main route of transmission of chronic hepatitis B is mother-to-child transmission(MTCT).Therefore,blocking MTCT of HBV is an important measure to prevent the occurrence and development of hepatitis B.This article is to review the related research on blocking HBV MTCT at home and abroad,hoping to provide help for clinical practice.
作者
孙芳芳
程澄
陆慧慧
曾湛
李明慧
谢尧
Sun Fangfang;Cheng Cheng;Lu Huihui;Zeng Zhan;Li Minghui;Xie Yao(Department of Hepatology Division 2,Beijing Ditan Hospital,Capital Medical University,Beijing 100015,China;Department of Hepatology Division 1,Beijing Ditan Hospital,Capital Medical University,Beijing 100015,China;Department of Hepatology Division 2,Peking University Ditan Teaching Hospital,Beijing 100015,China)
出处
《中华实验和临床病毒学杂志》
CAS
CSCD
2021年第4期472-475,共4页
Chinese Journal of Experimental and Clinical Virology
基金
首都临床特色应用研究专项(Z151100004015122)
北京市医院管理局临床医学发展专项(XMLX 201706)
国家科技重大专项(2018ZX10715-005-003-005)
北京市科技计划子课题(D161100002716002)
北京市医院管理中心消化内科学科协同发展中心资助课题(XXZ0302)。
