摘要
目的分析血清IFN-γ、IL-12水平预测喘息性支气管炎患儿复发的价值。方法回顾性分析,将2018年2月至2020年1月我院39例治疗后复发的喘息性支气管炎患儿资料纳入复发组,将同期39例治疗后未复发的喘息性支气管炎患儿资料纳入未复发组。记录两组患儿治疗前血清γ-干扰素(IFN-γ)、白细胞介素-12(IL-12)水平,分析二者预测喘息性支气管炎患儿复发的价值。结果复发组血清IFN-γ、IL-12水平均低于未复发组,差异有统计学意义(P<0.05);绘制ROC曲线,结果显示,喘息性支气管炎患儿治疗前血清IFN-γ、IL-12水平及联合预测喘息性支气管炎患儿复发的AUC>0.7,预测价值均理想,且以联合预测价值最佳。结论血清IFN-γ、IL-12水平预测喘息性支气管炎患儿复发的价值较高。
Objective To analyze the value of serum IFN-γ and IL-12 levels in predicting the recurrence of children with asthmatic bronchitis.Methods A retrospective analysis was performed,39 children with asthmatic bronchitis who recurred after treatment in our hospital from February 2018 to January 2020 were included in the recurrence group,the data of 39 children with asthmatic bronchitis who did not recur after treatment in the same period were included in the non recurrence group.The serum interferon-γ(IFN-γ),interleukin-12(IL-12)levels f children in the two groups were recorded before treatment,the value of the two in predicting the recurrence of children with asthmatic bronchitis was analyzed.Results The serum IFN-γ and IL-12 levels in the recurrence group were lower than those in the non recurrence group,the difference was statistically significant(P<0.05);the ROC curve was drawn,and the results showed that the AUC of serum IFN-γ,IL-12 levels before treatment alone and in combination for the prediction of recurrence in children with asthmatic bronchitis were>0.7,the prediction value was ideal,and the combined prediction value was the best.Conclusion The serum IFN-γ and IL-12 levels have higher value in predicting the recurrence of children with asthmatic bronchitis.
作者
徐奎
XU Kui(Luoyang Oriental Hospital Precision Medicine Center,Luoyang 471000 China)
出处
《内蒙古医学杂志》
2021年第9期1037-1039,共3页
Inner Mongolia Medical Journal
