摘要
目的:本研究旨在探讨幽门螺杆菌(Helicobacter pylori,Hp)感染对社区2型糖尿病患者血糖、血脂等指标的影响,为更好的控制2型糖尿病患者血糖水平寻找更多思路。方法:纳入104例2型糖尿病门诊患者,其中男性48名,女性56名,年龄为45~82岁,平均年龄为69.95岁。根据Hp感染情况分为Hp阳性和Hp阴性两组。比较两组患者的年龄、性别、体重指数、血糖、糖化血红蛋白(HbA1c)、血脂。结果:在2型糖尿病患者中检出Hp阳性者64例,检出率为61.5%。Hp阳性组患者的年龄低于阴性组[(67.5±7.29)岁比(69.95.00±4.05)岁,P<0.05]。阳性组平均HbA1c水平和三酰甘油水平高于阴性组[(7.69±1.40)%比(7.12±1.36)%,P<0.05和(1.64±0.65)mmol/L比(1.36±0.55)mmol/L,P<0.05],阴性组患者的HbA1c达标率高于阳性组(57.5%比32.8%,P<0.05)。结论:Hp感染影响2型糖尿病患者的血糖控制,有可能促进糖尿病的发展。
Objective:To explore the influence of helicobacter pylori(HP)infection on blood glucose,blood lipids and other indicators of type 2 diabetic patients in the community to find more ideas for better control of blood glucose levels in patients with type 2 diabetes.Methods:One hundred and four patients with type 2 diabetes were included in the study,there were 48 males and 56 females,and the age ranged from 45 to 82 years old,with an average age of 69.95 years old.According to HP infection,they were divided into the HP positive group and HP negative group.The age,gender,body mass index,blood glucose,glycosylated hemoglobin(HbA1c)and blood lipid of the two groups were compared.Results:In type 2 diabetes patients,64 cases of HP positive were detected,and the detection rate was 61.5%.The age of the patients in the HP positive group was lower than that in the negative group[(67.5±7.29)years to(69.95.00±4.05)years,P<0.05].The average HbA1c and triacylglycerol levels in the positive group were higher than those in the negative group[(7.69±1.40)%to(7.12±1.36)%,P<0.05 and(1.64±0.65)mmol/L to(1.36±0.55)mmol/L,P<0.05],the HbA1c compliance rate in the negative group was higher than that in the positive group(57.5%vs.32.8%,P<0.05).Conclusion:HP infection affects blood glucose control in type 2 diabetic patients,and may promote the development of diabetes.
作者
王万敏
尹相风
胡承伟
邹凡
WANG Wannmin;YIN Xiangfeng;HU Chengwei;ZOU Fan(General Practice Department of Changzheng Community Health Service Center of Putuo District,Shanghai 200333,China)
出处
《上海医药》
CAS
2021年第18期53-55,共3页
Shanghai Medical & Pharmaceutical Journal
关键词
幽门螺杆菌感染
2型糖尿病
血糖
糖化血红蛋白
血脂
helicobacter pylori infection
type 2 diabetes
plasma glucose
glycosylated hemoglobin
blood lipids