摘要
目的探讨肝硬化腹水患者的内科临床治疗效果。方法方便选取该院2018年8月—2019年8月收治98例肝硬化腹水患者,随机分组各49例,观察对照组(采取传统治疗方法)、研究组(采取内科治疗方法)的肝功能指标、治疗总有效率及不良反应率。结果治疗前,两组肝功能指标水平比较差异无统计学意义(t=0.078、0.239、0.046、0.330,P>0.05)。治疗后研究组的谷丙转氨酶为(60.15±2.13)U/L、谷草转氨酶为(44.87±1.17)U/L、γ-谷氨酰转肽酶为(16.52±2.14)g/L、总胆红素为(73.87±1.17)U/L,对照组的谷丙转氨酶为(72.17±4.65)U/L、谷草转氨酶为(60.85±1.15)U/L、γ-谷氨酰转肽酶为(21.35±2.25)g/L、总胆红素为(85.85±2.15)U/L,研究组的各项肝功能指标水平优于对照组,差异有统计学意义(t=16.451、68.185、10.888、34.260,P<0.05)。研究组治疗总有效率(95.92%)高于对照组(79.59%),差异有统计学意义(χ^(2)=6.080,P<0.05);研究组不良反应率(4.08%)低于对照组(16.33%),差异有统计学意义(χ^(2)=4.010,P<0.05)。结论内科临床治疗肝硬化腹水的效果确切且安全可靠。
Objective To explore the effect of medical clinical treatment in patients with liver cirrhosis and ascites.Methods conveniently selected 98 patients with liver cirrhosis and ascites were admitted to the hospital from August 2018 to August 2019,and 49 patients were randomly divided into groups.The liver function indexes,the total effective rate of treatment and adverse reaction rate of the control group(traditional treatment method)and the study group(medical treatment method)were observed.Results Before treatment,there was no statistically significant difference in liver function index levels between the two groups(t=0.078,0.239,0.046,0.330,P>0.05).After treatment,alanine aminotransferase in the study group was(60.15±2.13)U/L,aspartate aminotransferase was(44.87±1.17)U/L,γ-glutamyl transpeptidase was(16.52±2.14)g/L,total bile red pigment was(73.87±1.17)U/L,the alanine aminotransferase of the control group was(72.17±4.65)U/L,the aspartate aminotransferase was(60.85±1.15)U/L,and theγ-glutamyl transpeptidase was(21.35±2.25)g/L,total bilirubin was(85.85±2.15)U/L,the liver function index levels of the study group were better than those of the control group,the difference was statistically significant(t=16.451,68.185,10.888,34.260,P<0.05).The total effective rate of treatment in the study group(95.92%)was higher than that of the control group(79.59%),the difference was statistically significant(χ^(2)=6.080,P<0.05);the adverse reaction rate of the study group(4.08%)was lower than that of the control group(16.33%),the difference was statistically significant(χ^(2)=4.010,P<0.05).Conclusion The clinical effect of internal medicine in the treatment of cirrhotic ascites is accurate,safe.
作者
赵世俊
张佳妮
ZHAO Shijun;ZHANG Jiani(Department of Gastroenterology,Wuwei Liangzhou Hospital,Wuwei,Gansu Province,733099 China)
出处
《中外医疗》
2021年第19期21-24,共4页
China & Foreign Medical Treatment
基金
2015凉州区第一批科技计划项目(LZ150105)。
关键词
肝硬化腹水
内科临床治疗
疗效
Ascites due to liver cirrhosis
Clinical medical treatment
Curative effect
