摘要
目的探讨化瘀消痛汤联合小针刀对腰椎间盘突出症患者疼痛及血清肿瘤坏死因子-α(TNF-α)、前列腺素E2(PEG_(2))、白细胞介素-6(IL-6)水平的影响。方法回顾性分析昆明市中医医院2018年7月至2019年3月收治的114例腰椎间盘突出症患者的临床资料,按照治疗方法的不同分为A组(57例)和B组(57例)。A组患者采用小针刀治疗,B组患者在A组的基础上联合化瘀消痛汤治疗,两组患者均进行1个疗程(4周为1个疗程)的治疗。比较两组患者治疗后的临床疗效,治疗前后疼痛情况及血清TNF-α、PEG_(2)、IL-6水平。结果B组患者总有效率为89.47%,高于A组的75.44%;治疗后两组患者疼痛分级指数(PRI)、现时疼痛强度(PPI)、视觉模拟疼痛量表(VAS)评分及血清TNF-α、PEG_(2)、IL-6水平均较治疗前降低,且B组较A组低(均P<0.05)。结论化瘀消痛汤联合小针刀可有效改善腰椎间盘突出症患者临床症状,减轻机体炎症反应,降低患者疼痛感,提高治疗效果。
Objective To explore the effects of Huayu Xiaotong decoction combined with small needle knife on pain and serum tumor necrosis factor-α(TNF-α),prostaglandin E2(PEG_(2))and interleukin-6(IL-6)levels in patients with lumbar disc herniation.Methods A retrospective analysis of the clinical data of 114 patients with lumbar disc herniation admitted to Kunming Municipal Hospital of Traditional Chinese Medicine from July 2018 to March 2019 were divided into the group A(57 cases)and the group B(57 cases)according to different treatment methods.Patients in the group A were treated with a small needle knife,and patients in the group B were treated with Huayu Xiaotong decoction on the basis of the group A.Patients in both groups received 1 course of treatment(4 weeks as 1 course).The clinical effects of the two groups of patients after treatment were compared,the pain grading index(PRI),present pain intensity(PPI),visual analog pain scale(VAS)scores and serum TNF-α,PEG_(2) and IL-6 levels before and after treatment were compared.Results After treatment,the total effective rate of patients in the group B was 89.47%,which was higher than 75.44%in the group A;after treatment,the PRI,PPI,VAS scores and serum TNF-α,PEG_(2),IL-6 levels of the two groups were lower than those before treatment,and those of the group B were lower than those of the group A(all P<0.05).Conclusion Huayu Xiaotong decoction combined with small needle knife can effectively improve the clinical symptoms of patients with lumbar disc herniation,reduce the patient's pain,inhibit the body's inflammatory response,and improve the treatment effect.
作者
武水民
段生艳
WU Shuimin;DUAN Shengyan(Department of Orthopedics and Traumatology,Kunming Municipal Hospital of Traditional Chinese Medicine,Kunming,Yunnan 650011,China;Chinese Medicine School(College of Chinese Medicine),Baoshan College of Traditional Chinese Medicine,Baoshan,Yunnan 678099,China)
出处
《大医生》
2021年第9期1-4,共4页
Doctor
基金
云南省科技厅科技计划项目[编号:2019FF002(-027)]。
关键词
腰椎间盘突出症
化瘀消痛汤
小针刀
疼痛
炎性因子
Lumbar disc herniation
Huayu Xiaotong decoction
Small needle knife
Pain
Inflammatory factors
