摘要
目的:研究缩宫素联合麦角新碱治疗宫缩乏力性产后出血的效果。方法:选取上饶市立医院妇产科于2019年3月至2020年5月收治的宫缩乏力性产后出血患者100例,以随机数字表法分为对照组和观察组,各50例。对照组产妇使用缩宫素注射液,观察组在此基础上联合马来酸麦角新碱注射液。比较两组产妇临床疗效,产后2 h、6 h、24 h出血量,生产后1 d、3 d宫底高度,产后不良反应发生率及产妇生产前与分娩24 h后血红蛋白(Hb)水平及收缩压(SBP)、舒张压(DBP)与心率(HR)水平。结果:观察组产妇临床总有效率94.00%,高于对照组70.00%;且产后2 h、6 h、24 h出血量,产后3 d时宫底高度及不良反应发生率均低于对照组(P<0.05);两组产妇产前及产后24 h Hb水平及DBP、SBP与HR指标相比较差异均无统计学意义(P>0.05)。结论:缩宫素联合麦角新碱对宫缩乏力性产后出血具有更好的止血效果,能有效加快产妇恢复速度,且安全性能良好,治疗效果更佳。
Objective:To study the effect of oxytocin combined with ergonovine in the treatment of postpartum hemorrhage caused by uterine asthenia.Methods:Selected patients with postpartum hemorrhage due to uterine contraction and asthenia who were admitted to the Department of Obstetrics and Gynecology of Shangrao Municipal Hospital from March 2019 to May 2020 as the research object,100 cases in total,divided into control group and observation group by random number table method,50 cases each.Control group women use oxytocin injection,on this basis,the observation group combined with ergonovine maleate injection.Compare the clinical efficacy of the two groups,bleeding volume at 2 h,6 h,24 h postpartum,1 d,3 d after delivery height of the fundus,the incidence of postpartum adverse reactions and the levels of Hb and DBP,SBP and HR levels before delivery and 24 hours after delivery.Results:The total clinical effective rate of the observation group is 94.00%,70.00%higher than the control group;and the amount of bleeding 2 h,6 h,24 h postpartum,the height of the fundus of the uterus and the occurrence of adverse reactions at 3 days postpartum were lower than those of the control group(P<0.05);there was no statistically significant difference in Hb levels,DBP,SBP,and HR indicators between the two groups before and after delivery(P>0.05).Conclusion:The combination of oxytocin and ergonovine has a better hemostatic effect on postpartum hemorrhage caused by uterine contraction and asthenia,can effectively speed up maternal recovery,and good safety performance,better treatment effect.
作者
余淑勤
徐小翠
李梅荣
YU Shuqin;XU Xiaocui;LI Meirong(Shangrao Municipal Hospital,Shangrao Jiangxi 334000,China)
出处
《药品评价》
CAS
2021年第9期549-551,共3页
Drug Evaluation
基金
江西省卫生健康委科技计划项目(202140955)。
关键词
产后出血
宫缩乏力
缩宫素
麦角新碱
血红蛋白
Postpartum hemorrhage
Uterine contraction and asthenia
Oxytocin
Ergonovine
Hemoglobin
