摘要
目的:观察真武汤合血府逐瘀汤加减联合参芪扶正注射液治疗冠心病心力衰竭的临床疗效。方法:选取70例冠心病心力衰竭患者,按随机数字表法分为观察组和对照组各35例。对照组给予规范化的西医内科标准方案进行治疗,观察组在对照组基础上加用真武汤合血府逐瘀汤、参芪扶正注射液治疗。比较2组临床疗效、心功能参数及血清N末端B型利钠肽原(NT-proBNP)水平。结果:观察组总有效率为97.14%,对照组为82.86%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组左室射血分数(LVEF)、左室收缩末期容积(LVESV)以及左室舒张末期容积(LVEDV)比较,差异无统计学意义(P>0.05)。治疗后,2组LVEF较治疗前上升,LVESV、LVEDV较治疗前下降;且观察组LVEF上升幅度大于对照组,LVESV、LVEDV降低幅度大于对照组;差异均有统计学意义(P<0.05)。治疗前,2组血清NT-proBNP水平比较,差异无统计学意义(P>0.05)。治疗后,2组血清NT-proBNP水平较治疗前下降,且观察组血清NT-proBNP水平降低幅度大于对照组,差异均有统计学意义(P<0.05)。结论:真武汤合血府逐瘀汤加减联合参芪扶正注射液治疗冠心病心力衰竭可以提高临床治疗效果,改善患者心功能。
Objective:To observe the clinical effect of modified Zhenwu tang and Xuefu Zhuyu tang combined with Shenqi Fuzheng injection for coronary artery disease complicated with heart failure. Methods: A total of 70 cases of patients with coronary artery disease complicated with heart failure were selected and divided into the observation group and the control group according to the random number table method,35 cases in each group.The control group was treated with standard scheme for internal medicine of western medicine,and the observation group was additionally treated with modified Zhenwu tang and Xuefu Zhuyu tang combined with Shenqi Fuzheng injection based on the treatment of the control group.The clinical effect,indexes of the heart function,and levels of N-terminal pro B-type natriuretic peptide(NT-proBNP) were compared between the two groups. Results: The total effective rate was 97.14% in the observation group and 82.86% in the control group,the difference being significant(P<0.05).Before treatment,when compared left ventricular ejection fraction(LVEF),left ventricular end-systolic volume(LVESV) and left ventricular end-diastolic volume(LVEDV) between the two groups,there was no significance being found in the difference(P>0.05).After treatment,LVEF in the two groups was increased when compared with that before treatment,and LVESV and LVEDV were decreased;the increase of LVEF as well as the decrease of LVESV and LVEDV in the observation group was larger than that in the control group,differences being significant(P<0.05).Before treatment, there was no significant difference being found in the comparison of levels of NT-proBNP in serum between the two groups(P>0.05).After treatment,levels of NT-proBNP in serum in the two groups were decreased when compared with those before treatment,and the decrease in the observation group was larger than that in the control group,differences being significant(P<0.05). Conclusion: In the treatment of coronary artery disease complicated with heart failure,the therapy of modifi
作者
朱航
赵建波
王长江
ZHU Hang;ZHAO Jianbo;WANG Changjiang
出处
《新中医》
CAS
2021年第11期23-26,共4页
New Chinese Medicine
关键词
冠心病
心力衰竭
真武汤
血府逐瘀汤
参芪扶正注射液
心功能
N末端B型利钠肽原
Coronary artery disease
Heart failure
Zhenwu tang
Xuefu Zhuyu tang
Shenqi Fuzheng injection
Heart function
N-terminal pro B-type natriuretic peptide
