摘要
目的探讨终末期肾病透析治疗患者肾性贫血的发生状况及其影响因素。方法回顾性分析2016年6月至2018年6月在山西省煤炭中心医院行维持性血液透析治疗的70例终末期肾病患者的临床资料。入院后评估患者肾性贫血的发生状况,统计患者的基线资料,分析终末期肾病透析治疗患者发生肾性贫血的影响因素。结果70例终末期肾病透析治疗患者中52例发生肾性贫血,发生率为74.29%(52/70)。发生肾性贫血的终末期肾病透析治疗患者是否使用铁剂、每周红细胞生成素(EPO)使用量、尿素清除指数(Kt/V)值与未发生肾性贫血的终末期肾病透析治疗患者比较,差异有统计学意义(P<0.05);其他基线资料比较,差异未见统计学意义(P>0.05)。经Logistic回归分析结果显示,未使用铁剂、每周EPO使用量较少、Kt/V值较低均可能是终末期肾病透析治疗患者发生肾性贫血的影响因素(OR>1,P<0.05)。结论终末期肾病透析治疗患者肾性贫血发生率较高,未使用铁剂、每周EPO使用量较少、Kt/V值较低均可能会增加其发生肾性贫血的风险,可针对性进行干预来纠正患者肾性贫血情况。
Objective To investigate the incidence and influencing factors of renal anemia in patients with end-stage renal disease(ESRD)treated by dialysis.Methods The clinical data of 70 ESRD patients treated by maintenance hemodialysis in Shanxi Coal Central Hospital from June 2016 to June 2018 were retrospectively analyzed.After admission,the incidence of renal anemia was evaluated,and the baseline data of patients were collected.The influencing factors of renal anemia in patients with end-stage renal disease undergoing dialysis treatment were analyzed.Results Among the 70 patients with ESRD treated by dialysis,52 patients had renal anemia,and the incidence was 74.29%(52/70).There were significant differences in using of iron supplement,weekly erythropoietin(EPO)usage,and urea clearance index(Kt/V)value between ESRD patients with renal anemia and ESRD patients without renal anemia(P<0.05).There was no statistically significant difference in other baseline data between ESRD patients with and without renal anemia(P>0.05).Logistic regression analysis showed that the factors influencing renal anemia in patients with end-stage renal dialysis were no iron supplement,less EPO usage per week,and low Kt/v value(OR>1,P<0.05).Conclusions The incidence of renal anemia in ESRD dialysis patients is high.The risk of renal anemia may be increased by not using iron supplement,less weekly EPO usage,and low Kt/V value.Targeted intervention can be carried out to correct the situation of renal anemia.
作者
郑世荣
Zheng Shirong(Department of Nephrology,Shanxi Coal Central Hospital,Taiyuan 030006,China)
出处
《中国实用医刊》
2021年第9期48-50,共3页
Chinese Journal of Practical Medicine
关键词
终末期肾病
血液透析
肾性贫血
End-stage renal disease
Hemodialysis
Renal anemia
