摘要
目的研究分析缺血性脑血管病(ICVD)血清尿酸的水平与颈动脉不稳定斑块的关系及与临床意义。方法选取2018年1月至2019年6月我院住院ICVD患者248例,分为短暂性脑缺血(TIA)组、脑梗死组,入院24~72 h后行颈动脉超声检查,并于入院次日抽取静脉血,应用ELASA法测定尿酸含量。结果随着血清中尿酸浓度增高,颈动脉内膜不稳定斑块面积也增大(P<0.05),且脑梗组血尿酸水平高于TIA组(P<0.05)。结论尿酸可致颈动脉内膜不稳定斑块面积增大,从而进一步导致缺血性脑血管病的发生。
Objective To study the relationship between serum uric acid level and carotid artery unstable plaque in patients with ischemic cerebrovascular disease(ICVD)and its clinical significance.Methods Two hundred and forty-eight patients with ICVD in our hospital from January 2018 to June 2019 were selected and divided into transient cerebral ischemia(TIA)group and cerebral infarction group.Carotid artery ultrasound examination was performed 24-72 hours after admission,and venous blood was taken on the next day after admission.The content of uric acid was determined by elasa method.Results With the increase of serum uric acid concentration,the area of unstable plaque in carotid intima increased(P<0.05),and the serum uric acid level in cerebral infarction group was higher than that in TIA group(P<0.05).Conclusion Uric acid can increase the area of unstable plaque in carotid intima,which further leads to the occurrence of ischemic cerebrovascular disease.
作者
葛秋影
荣阳
荣根满
GE Qiuying;RONG Yang;RONG Genman(Department of Neurology,Liaoyang Central Hospital,Liaoyang 111000,China;Medical Department of Liaoyang Central Hospital,Liaoyang 111000,China;China Railway 19^(th)Bureau Group Central Hospital Medical Service Branch,Liaoyang 111000,China)
出处
《中国医药指南》
2021年第13期85-86,共2页
Guide of China Medicine
关键词
缺血性脑血管病
尿酸
颈动脉斑块
临床分析
Ischemic cerebrovascular disease
Uric acid
Carotid plaque
Clinical analysis
