摘要
目的观察腹四针及骶四针联合中药灌肠对慢性盆腔炎患者盆底肌电、炎症介质和免疫功能的影响。方法选取159例慢性盆腔炎患者作为研究对象,随机分为对照1组、对照2组和观察组,每组53例。对照1组仅采用西医治疗,对照2组患者在对照1组治疗的基础上采用中药灌肠的方法,观察组患者在对照2组治疗的基础上采用腹四针及骶四针联合治疗。比较3组患者的临床疗效、盆底肌电、炎症介质、免疫功能。结果观察组总有效率(94.3%)显著高于对照1组(49.1%)和对照2组(73.6%)(P<0.05)。治疗后,观察组患者的盆底肌肌电位和盆底疲劳值优于对照1组和对照2组(P<0.05);观察组各项炎症因子水平均优于对照1组和对照组2组(P<0.05);观察组CD8^(﹢)水平与对照1组和对照2组比较,差异无统计学意义(P>0.05),观察组CD4^(﹢)、CD4^(﹢)/CD8^(﹢)水平均优于对照组1组和对照2组(P<0.05)。结论在西医治疗的基础上,腹四针及骶四针联合中药灌肠可显著提高慢性盆腔炎的临床疗效,同时对患者体内炎症因子有较好的抑制作用,对患者的免疫功能有着积极作用。
Objective To observe the effect of abdominal four-needle and sacral four-needle eletroacupuncture plus Chinese herbal enema on pelvic floor myoelectricity, inflammatory mediators and immune function in patients with chronic pelvic inflammation. Method One hundred and fifty-nine patients with chronic pelvic inflammation were enrolled as subjects and randomized to control 1, control 2 and observation groups, with 53 cases in each group. Control 1 group received Western medical treatment;control 2 group, Chinese herbal enema in addition to what was given to control 1 group;the observation group, abdominal four-needle and sacral four-needle eletroacupuncture in addition to what was given to control 2 group. The clinical efficacy, pelvic floor myoelectricity, inflammatory mediators and immune functions were compared between the three groups. Result The total efficacy rate was significantly higher in the observation group(94.3%) than in control 1 group(49.1%) and control 2 group(73.6%)(P<0.05). After treatment, pelvic floor myoelectric potential and fatigue value were better in the observation group of patients than in control 1 and control 2 groups(P<0.05);inflammatory mediator levels were better in the observation group than in control 1 and control 2 groups(P<0.05);CD8+ levels had no statistically significant differences between the two groups(P>0.05);CD4+ and CD4+/CD8+ levels were better in the observation group than in control 1 and control 2 groups(P<0.05). Conclusion Abdominal four-needle and sacral four-needle eletroacupuncture plus Chinese herbal enema on the basis of Western medical treatment can markedly improve the clinical therapeutic effect of chronic pelvic inflammation. Meanwhile, it has a better inhibitory effect on inflammatory mediators and a active effect on immune function in the patients.
作者
魏慧俊
闫绍颖
尹艳茹
李金霞
王娅玲
段志芳
WEI Hui-jun;YAN Shao-ying;YIN Yan-ru;LI Jin-xia;WANG Ya-ling;DUAN Zhi-fang(Zhejiang University of Traditional Chinese Medicine Huzhou Hospital of Traditional Chinese Medicine,Huzhou 313000,China)
出处
《上海针灸杂志》
2021年第5期585-589,共5页
Shanghai Journal of Acupuncture and Moxibustion
基金
2020年度浙江省中医药科学研究基金项目(A类)(2020ZA111)。
关键词
针刺疗法
电针
腹四针
骶四针
灌肠
盆腔炎
Acupuncture therapy
Eletroacupuncture
Abdominal four-needle eletroacupuncture
Sacral four-needle eletroacupuncture
Enema
Pelvic inflammatory disease
