摘要
目的收集和统计临床送检样本ACTH项目的检测数据,根据不同疾病类型患者ACTH测值阳性率的水平,探讨ACTH检测在高血压、糖尿病及矮小症诊断中的意义。方法通过化学发光免疫分析法检测临床样本中的ACTH的浓度水平,并按临床样本的疾病类型进行分组,利用EXCEL软件对不同组患者样本阳性水平进行统计分析。结果在15 508例送检患者样本中,共检出1 635例ACTH阳性样本,其中有261例为高血压病人,398例为糖尿病病人,93例为矮小症病人,140例为肾病病人,70例为脑损伤病人,101例为垂体疾病病人,90例为肺病病人,482例为其他类型样本,阳性率分别为10.06%、9.26%、7.53%、14.94%、14.46%、23.71%、22.90%、9.38%。结论 ACTH检测对继发性高血压、糖尿病的诊断非常有必要,引起矮小症的病因较多,其中库欣病作为矮小症的病因比较罕见。
Objective The ACTH test data of clinical samples were collected and counted,and the significance of ACTH test in the diagnosis of hypertension,diabetes and short stature was discussed according to the positive rate of ACTH test in patients with different disease types. Methods The concentration of ACTH in clinical samples was detected by chemiluminescence immunoassay,and the patients were divided into groups according to the disease types of clinical samples. The positive levels of samples in different groups were analyzed by Excel software. Results Among 15 508 samples,1 635 samples were positive for ACTH. including 261 cases were hypertension,398 cases were diabetes,93 cases were dwarfism,140 cases were nephropathy,70 cases were brain injury,101 cases were pituitary disease,90 cases of pulmonary disease and 482 cases of other types of samples,The positive rates were 10. 06%,9. 26%,7. 53%,14. 94%,14. 46%,23. 71%,22. 90% and 9. 38% respectively. Conclusion ACTH detection is very necessary for the diagnosis of secondary hypertension and diabetes. There are many causes of dwarfism,among which Cushing’s disease is rare.
作者
周文军
何凤萍
杨祥康
ZHOU Wen-jun;HE Feng-ping;YANG Xiang-kang(Zhoushan Maternal and Child Health Care Hospital,Zhoushan,Zhejiang 316000,China)
出处
《中国卫生检验杂志》
CAS
2021年第6期756-757,760,共3页
Chinese Journal of Health Laboratory Technology
关键词
促肾上腺皮质激素
高血压
糖尿病
矮小症
Adrenocorticotropic hormone
Hypertension
Diabetes
Short stature
