摘要
目的比较阿替普酶与尿激酶治疗急性脑梗死患者的临床效果。方法选取2016年10月至2019年3月本院收治的89例急性脑梗死患者,依据入院先后时间分为实验组(n=45)与对照组(n=44)。实验组采用阿替普酶治疗,对照组采用尿激酶治疗,比较两组治疗效果、NIHSS及ADL评分、并发症发生率。结果两组治疗总有效率比较差异有统计学意义(P<0.05);治疗后,两组NIHSS、ADL评分比较差异有统计学意义(P<0.05);两组并发症总发生率比较差异有统计学意义(P<0.05)。结论对急性脑梗死患者应用阿替普酶治疗效果较好,能显著减轻患者神经缺损程度,提升患者日常生活能力,降低并发症发生率,提高患者生命质量,值得临床推广应用。
Objective To compare the clinical effects of alteplase and urokinase in patients with acute cerebral infarction.Methods 89 patients with acute cerebral infarction in our hospital were selected from October 2016 to March 2019.They were divided into experimental group(n=45)and control group(n=44)according to the time of admission.The experimental group was treated with alteplase and the control group was treated with urokinase.The treatment effect,NIHSS and ADL scores,and the incidence of complications were compared between the two groups.Results There was significant difference in the total effective rate between the two groups(P<0.05).After treatment,the difference was significant in the NIHSS and ADL scores between the two groups(P<0.05).The total incidence of complications between the two groups was statistically significant(P<0.05).Conclusion The application of alteplase to patients with acute cerebral infarction has a good treatment effect,which can significantly reduce the degree of neurological deficits,improve the ability of daily living of patients,reduce the occurrence of complications,and improve the quality of life of patients.It is worth promoting and applying.
作者
陈静晶
CHEN Jingjing(Department of Neurology,Zhuanghe Central Hospital,Dalian,Liaoning,116400,China)
出处
《当代医学》
2021年第12期25-27,共3页
Contemporary Medicine
关键词
脑梗死
急性
阿替普酶
尿激酶
神经缺损程度
Cerebral infarction
Acute
Alteplase
Urokinase
Degree of nerve defect
