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脓毒症肠屏障损伤"肺肠合治"思路研究 被引量:10

Study on idea of"combined treatment of lung and intestine"for intestinal barrier injury in sepsis
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摘要 以中医经典理论为指导,探讨脓毒症肠屏障损伤"肺肠合治"?临证思路.通过梳理祖国医学关于"肺与大肠相表里"经典论述,以现代医学对"肺肠功能密切相关性"的研究为基础,结合临证实践经验,总结出脓毒症肠屏障损伤的临床表现为邪毒壅盛、热结肠腑,实证为多见;其主要病机是肺与大肠气机失调,肺气失去宣降,胃肠通降作用失常,肺经及大肠经两经受累,为肺肠同病;治疗以"肺肠合治"为宜.本文为阐释中医药干预脓毒症肠屏障损伤提供了临证思路. This article was guided by the classic theory of traditional Chinese medicine(TCM),involving the investigation of the clinical thinking related to"combined treatment of lung and intestine"for intestinal barrier injury in sepsis.Through discussing the classical theory of"the lung and the large intestine being interiorly and exteriorly related"in TCM,based on the research of"close relationship between lung and intestine functions"in modern medicine and combined with clinical practical experiences,it was summarized that the clinical manifestations of intestinal barrier injury in sepsis were exuberant evil and toxin,heat binding in intestinal viscera and the repletion pattern being more commonly seen;the main pathogenesis was the imbalance of lung and large intestine qi,loss of lung qi diffusing and down-bearing and abnormality of gastrointestinal free down-bearing,indicating the involvement of both lung and large intestine meridians or in other words simultaneous onset of lung and intestine diseases.The proper management of the disease should be combined treatment for both lung and intestine disorders.This article provided a clinical thinking route for the intervention of TCM for intestinal barrier injury in sepsis.
作者 李兰 吕波 陈立 廖前花 雷宽素 Li Lan;Lyu Bo;Chen Li;Liao Qianhua;Lei Kuansu(department of Critical Care Medicine,the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang 550001,Guizhou,China;Guizhou University of Traditional Chinese Medicine^Guiyang 550001,Guizhou,China)
出处 《中国中西医结合急救杂志》 CAS CSCD 北大核心 2021年第1期5-7,共3页 Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
基金 国家自然科学軽(81860846) 国家中医药管理局第二届国医大师传承工作室建设项目(2015-24)。
关键词 肺与大肠相表里 肺肠合治 脓毒症肠屏障损伤 临证思路 Lung associated with the large intestine Combined treatment of lung and intestine Intestinal barrier injury in sepsis Clinical thinking
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