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老年肺动脉高压患者呼吸衰竭采用无创机械通气的效果

Effect of Non-invasive Mechanical Ventilation in Elderly Patients with Pulmonary Hypertension with Respiratory Failure
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摘要 目的分析无创机械通气在老年肺动脉高压患者呼吸衰竭中的应用效果。方法随机选取2016年7月-2019年7月期间该院收治的老年肺动脉高压呼吸衰竭患者80例,按照随机选取方式进行分组,分成观察组与对照组,两组各40例,对照组采用有创机械通气治疗,观察组采取无创机械通气治疗,对比两组不同治疗方式的临床效果。结果观察组患者治疗后的血气分析动脉血氧分压(87.6±4.5)mmHg、动脉血二氧化碳分压(45.2±1.1)mmHg、肺功能FEV1/FVC(88.2±3.8)%、PEF(5.9±1.2)L/s指标及肺动脉压(PASP)(42.9±3.2)cmH2O与对照组患者血气分析动脉血氧分压(69.8±2.8)mmHg、动脉血二氧化碳分压(55.3±1.5)mmHg、肺功能FEV1/FVC(72.6±2.9)%、PEF(5.1±0.9)L/s指标及肺动脉压(PASP)(54.2±4.6)cmH2O数据比较存在显著优势,且观察组患者最终治疗总有效率达到了95.0%,不良反应发生率仅为5.0%,与对照组指标的80.0%和20.0%存在显著优势,组间数据差异有统计学意义(t=21.241、34.341、20.640、3.373、12.754,χ^(2)=4.114、4.114,P<0.05)。结论应用无创机械通气治疗老年肺动脉高压呼吸衰竭的临床效果显著,可有效提高临床治疗效果及患者肺功能指标,降低肺动脉压及不良反应发生率。 Objective To analyze the effect of non-invasive mechanical ventilation in the treatment of respiratory failure in elderly patients with pulmonary hypertension.Methods A random selection of 80 elderly patients with pulmonary hypertension and respiratory failure in the hospital from July 2016 to July 2019 were randomly selected and divided into observation and control groups with 40 cases in each group.The control group adopted invasivemechanical ventilation treatment,the observation group was treated with non-invasive mechanical ventilation,and the clinical effects of different treatment methods were compared between the two groups.Results Blood gas analysis of the observation group after treatment.Arterial partial oxygen pressure(87.6±4.5)mmHg,arterial carbon dioxide partial pressure(45.2±1.1)mmHg,lung function FEV1 FVC(88.2±3.8)%,PEF(5.9±1.2)L/s index and pulmonary arterial pressure(PASP)(42.9±3.2)cmH2 O and control group blood gas analysis arterial partial oxygen pressure(69.8±2.8)mmHg,arterial carbon dioxide partial pressure(55.3±1.5)mmHg,lung function FEV1/FVC(72.6±2.9)%,PEF(5.1±0.9)L/s index,and pulmonary artery pressure(PASP)(54.2±4.6)cm H2 O data had significant advantages,and the total effective rate of the final treatment of the observation group reached95.0%,and adverse reactions incidence rate was only 5.0%,which was significantly superior to the 80.0%and 20.0%of the control group indicators.The data difference between the groups was statistically significant(t=21.241,34.341,20.640,3.373,12.754,χ^(2)=4.114,4.114,P<0.05).Conclusion The clinical effect of noninvasive mechanical ventilation in the treatment of elderly patients with pulmonary hypertension and respiratory failure is significant.It can effectively improve the clinical treatment effect and the patient’s pulmonary function indexes,reduce the pulmonary artery pressure and the incidence of adverse reactions.It is recommended to be popularized.
作者 高辉 杨丰鹤 高炜 GAO Hui;YANG Feng-he;GAO Wei(Department of Respiratory Medicine,Beijing Renhe Hospital,Beijing,102600 China)
出处 《中外医疗》 2021年第3期49-51,共3页 China & Foreign Medical Treatment
关键词 老年 肺动脉高压 呼吸衰竭 无创机械通气 效果分析 Elderly Pulmonary hypertension Respiratory failure Non-invasive mechanical ventilation Effect analysis
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