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长期无创通气对重度COPD稳定期疗效分析 被引量:6

Long term noninvasive positive pressure ventilation in patients with severe stable chronic obstructive pulmonary disease
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摘要 目的评价重度慢性阻塞性肺部疾病(COPD)稳定期进行无创通气的治疗效果。方法按时间顺序收集9例在我院呼吸科就诊并确诊为重度COPD患者的临床资料作回顾性分析。随访3年,其中观察组4例为B iPAP呼吸机治疗加长期家庭氧疗,对照组5例为单纯长期家庭氧疗,观察症状,收集患者的肺功能、动脉血气分析及住院次数数据。结果呼吸机治疗加长期家庭氧疗组患者,体力、肺功能及动脉血气分析均明显改善,住院次数明显下降,优于单纯长期家庭氧疗组患者。结论重度COPD稳定期患者,长期无创通气效果显著,生活质量明显改善。 Objective To evaluate the therapeutic effect of noninvasive positive pressure ventilation (NPPV) application in patiens with stable severe chronic obstructive pulmonary disease(COPD). Methods According to chronologicaol order,collected the clinical data of 9 patients with COPD final diagnosed and analysed retrospectively. Followed - up for 3 years, 4 cases were treated with NPPV plus long - term oxygen therapy (LTOT) ,5 cases by simple LTOT. Collected pulmonary function, arterial blood gas analysis data and analyzed. Results Effects of treatment group showed difference in blood gas, dyspnoea, sleep efficiency and health - related quality of life compared with LTOT group. Times of hospitalization descent was apparent. After this period dyspnoea decreased and health - related quality of life improved in the NPPV compared to the LTOT . Conclusion Long term therapeutic effect of NPPV application in patiens with stable severe COPD, quality of life improve significantly.
出处 《中原医刊》 2006年第14期9-11,共3页 Central Plains Medical Journal
关键词 慢性阻塞性肺部疾病 无创通气 稳定期 Chronic obstructive pulmonary disease Noninvasive positive pressure ventilation Stationary phase
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  • 1慢性阻塞性肺疾病(COPD)诊治规范(草案)[J].中华结核和呼吸杂志,1997,20(4):199-203. 被引量:1381
  • 2叶任高,陆再英主编..内科学[M].北京:人民卫生出版社,2004:1030.
  • 3Carrey Z,Gottfried SB, Levy RD. Ventilatory muscle support in respiratory failure with nasal positive pressure ventilation. Chest, 1990,97 :150-158. 被引量:1
  • 4Randerath WJ, Galetke W, Ruhle KH. Auto -adjusting CPAP based on impedance versus bilevel pressure in difficult - to - treat sleep apnea syndrome: a prospective randomized crossover study. Nihoa Kokyuki Gakkai, 2002,40( 11 ) :845 - 850. 被引量:1

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