摘要
目的:研究乌鸦果Vaccinium fragile Franch.地上部分的化学成分。方法:采用D101大孔树脂、正相硅胶、半制备液相色谱分离纯化,采用1H-NMR、13C-NMR等波谱技术进行结构鉴定。结果:从乌鸦果地上部分中分离得到13个化合物,分别鉴定为:蒲公英萜醇(1)、乙酰乌索酸(2)、乌索酸(3)、山楂酸(4)、科罗索酸(5)、阿江榄仁酸(6)、铁冬青酸(7)、1β-羟基蔷薇酸(8)、19,23,24-trihydroxy-3-oxours-12-en-28-oic acid(9)、2α,3α,19α,23-tetrahydroxyurs-12-en-28-oic acid(10)、积雪草酸(11)、urs-12-ene-2α,3β,28-triol(12)、蔷薇酸(13)。结论:以上化合物均为首次从该植物中分离得到,其中,化合物2、6~12为首次从越桔属植物中分离得到。
Objective:To study the chemical constituents from the aboveground part of Vaccinium fragile.Methods:The chemical constituents were isolated and purified by chromatography on D101 macroporous resin,silica gel,and semi-preparative HPLC,their structures were identified by 1H-NMR and 13C-NMR.Results:Thirteen compounds were isolated from the aboveground part of Vaccinium fragile and identified as taraxerol(1),acetylursolic acid(2),ursolic acid(3),maslinic acid(4),corosolic acid(5),arjunolic acid(6),rotundic acid(7),1β-hydroxyeuscaphic acid(8),19,23,24-trihydroxy-3-oxours-12-en-28-oic acid(9),2α,3α,19α,23-tetrahydroxyurs-12-en-28-oic acid(10),asiatic acid(11),urs-12-ene-2α,3β,28-triol(12),euscaphic acid(13),respectively.Conclusion:The thirteen compounds are isolated from this plant for the first time,among them,compounds 2,6 to 12 are isolated from the genus for the first time.
作者
颜智
邱明华
李忠荣
刘育辰
YAN Zhi;QIU Ming-hua;LI Zhong-rong;LIU Yu-chen(Guizhou University of Traditional Chinese Medicine,Guiyang 550025,China;Kunming Institute of Botany,Chinese Academy of Scisences,Kunming 650201,China)
出处
《中药材》
CAS
北大核心
2020年第4期858-861,共4页
Journal of Chinese Medicinal Materials
基金
中国科学院昆明植物研究所特色研究所建设自主项目(KIB-ZZ-2016B03)。
关键词
乌鸦果
化学成分
结构鉴定
Vaccinium fragile Franch.
Chemical constituents
Structural identification
