摘要
目的探讨血压控制良好的原发性高血压患者颈动脉脉搏波传导速度的影响因素。方法选取血压控制良好的137例原发性高血压病患者为研究对象,分别以收缩起始脉搏波传导速度(PWV-BS)平均值和收缩末期脉搏波传导速度(PWV-ES)平均值为界分为高PWV-BS组、低PWV-BS组和高PWV-ES组、低PWV-ES组,检测并对比高、低PWV-BS组及高、低PWV-ES组性别、年龄、身高、体重、BMI、吸烟史、在院期间的空腹血糖(FPG)、低密度脂蛋白(LDL)、收缩压(SBP)及舒张压(DBP),并分析PWV-BS及PWV-ES的影响因素。结果高PWV-BS组年龄、BMI、吸烟史人数、LDL及SBP明显高于低PWV-BS组,高PWV-ES组年龄、体重、BMI、吸烟史人数、LDL及SBP明显高于低PWV-ES组,差异有统计学意义(P<0.05)。多元逐步回归分析发现,影响PWV-BS的危险因素为年龄、吸烟史,影响PWV-ES的危险因素为性别、年龄、吸烟史和SBP(P<0.05)。结论控制血压还应注意危险因素进行调整治疗,从而进一步改善动脉弹性及患者预后。
Objective To investigate the influencing factors of carotid-femoral pulse wave velocity(cfPWV)in patients with essential hypertension with well controlled.Methods A total of 137 essential hypertension patients with well blood pressure controlled were selected and divided into the high pulse wave velocity-beginning of systole(PWV-BS)group,the low PWV-BS group and the high pulse wave velocity-end of systole(PWV-ES)group,the low PWV-ES group according to their mean value of PWV-BS and PWV-ES.Compared gender,age,height,weight,BMI,smoking history,fasting plasma glucose(FPG),low-density lipoprotein(LDL),systolic blood pressure(SBP)and diastolic blood pressure(DBP)between the high PWV-BS group and the low PWV-BS group,and between the high PWV-ES group and the low PWV-ES group,then analyzed the influencing factors of PWV-BS and PWV-ES.Results Age,BMI,smoking history,LDL and SBP of the high PWV-BS group were significantly higher than those of the low PWV-BS group.Age,weight,BMI,smoking history,LDL and SBP of the high PWV-ES group were significantly higher than those of the low PWV-ES group(P<0.05).Multivariate stepwise regression analysis showed that age and smoking history were the risk factors for PWV-BS;gender,age,smoking history and SBP were the risk factors for PWV-ES(P<0.05).Conclusion For controlling blood pressure,attention should be paid to these factors and adjust the treatment plan in order to further improve arterial elasticity and prognosis of patients.
作者
丁钱山
朱正球
王晗
刘福明
邹冲
黄辉
DING Qianshan;ZHU Zhengqiu;WANG Han;LIU Fuming;ZOU Chong;HUANG Hui(Department of Ultrasound Medicine,Jiangsu Provincial Hospital of Traditional Chinese Medicine/Affiliated Hospital of Nanjing University of Traditional Chinese Medicine,Nanjing,Jiangsu 210029,China;Department of Geriatrics,Jiangsu Provincial Hospital of Traditional Chinese Medicine/Affiliated Hospital of Nanjing University of Traditional Chinese Medicine,Nanjing,Jiangsu 210029,China;Department of Cardiovascular Medicine,Jiangsu Provincial Hospital of Traditional Chinese Medicine/Affiliated Hospital of Nanjing University of Traditional Chinese Medicine,Nanjing,Jiangsu 210029,China)
出处
《重庆医学》
CAS
2021年第4期605-608,共4页
Chongqing medicine
基金
江苏省“六大人才高峰”科技项目(WSN-091)
江苏省干部保健科研项目(BJ16021)
江苏省第十六批“六大人才高峰”创新人才团队项目(TD-SWYY-069)
江苏省中管局中医药科技发展计划重点项目(ZD201906)。
关键词
脉搏波分析
高血压
颈动脉
收缩起始脉搏波速度
收缩末期脉搏波速度
pulse wave analysis
hypertension
carotid arteries
pulse wave velocity-beginning of systole
pulse wave velocity-end of systole
