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老年中心动脉和肱动脉血压差值与冠状动脉病变程度的研究 被引量:2

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摘要 目的探讨冠心病患者中心动脉-肱动脉差值及动脉弹性,评价冠心病相关危险因素。方法选取2018年3月~2020年2月于我院老年病科以冠心病不稳定性心绞痛入院完成冠状动脉造影术患者416例,根据患者症状和冠状动脉造影结果分为冠心病组276例和对照组140例,收集一般临床资料,测量空腹血糖、糖化血红蛋白(HbA1C)、N末端B型钠尿肽前体(NT-proBNP)、尿酸等。采用超声心动图检查左心室质量指数(LVMI)。多功能血管病变检测仪测定踝肱指数(ABI)、肱踝脉搏波传导速度(baPWV)。冠状动脉造影术检查中心动脉收缩压,计算中心动脉与肱动脉收缩压血压差值(ΔSBP)等,应用Gensini积分法评价冠状动脉病变程度。用多因素logistic回归分析。结果冠心病组脂肪肝、高血压、高尿酸血症、糖尿病、血管内斑块、血压差值<10 mm Hg(1 mm Hg=0.133 kPa)比例、空腹血糖、HbA1C、NT-proBNP、尿酸、中心动脉收缩压、中心动脉脉压差、LVMI、Gensini积分、baPWV高于对照组(P<0.01),△SBP、ABI明显低于对照组(P<0.01)。多因素logistic回归分析显示,血压差值<10 mm Hg、baPWV、LVMI、血管内斑块(颈部/下肢)及高尿酸血症为冠心病危险因素(95%CI:5.095~27.963,P=0.000;95%CI:10.629~256.285,P=0.001;95%CI:1.042~1.088,P=0.000;95%CI:2.996~21.376,P=0.000;95%CI:2.825~35.634,P=0.004)。结论老年冠心病患者存在心室重构,动脉弹性、中心动脉-肱动脉血压差值<10 mm Hg可能为冠心病的危险因素。
出处 《中华老年心脑血管病杂志》 北大核心 2021年第4期427-429,共3页 Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金 天津市第一中心医院科技基金项目(院CF201821)。
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