摘要
目的:通过分析残余胆固醇(RC)在急性冠脉综合征(ACS)患者中的变化,研究残余胆固醇与急性冠脉综合征发病的相关性。方法:选取2017年1月至2018年2月于我院心内科住院并诊断为急性冠脉综合征的患者共300例作为研究对象,依据诊断标准将ACS患者分为急性ST段抬高型心肌梗死组(STEMI组),急性非ST段抬高型心肌梗死组(NSTEMI组),不稳定型心绞痛组(UA组),三病例组研究对象的数量分别为108例、88例和104例。选取同期我院急诊科就诊非急性冠脉综合征的胸痛患者100例作为非ACS组。收集研究对象的临床相关资料,比较四组血脂的水平差异。结果:STEMI组、NSTEMI组、UA组血总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)和残余胆固醇(RC)水平均高于非ACS组,差异具有统计学意义(P<0.05)。高密度脂蛋白胆固醇(HDL-C)和非高密度脂蛋白胆固醇(non-HDL-C)差异不具有统计学意义(P>0.05)。ROC中RC曲线下面积为0.710,高于其他血脂指标。结论:RC与急性冠脉综合征发病有关,且在急性心肌梗死诊断中有一定的预测价值。
Objective:To analyze the changes of residual cholesterol(RC)in patients with acute coronary syndrome(ACS)and study the relevance of RC to ACS.Methods:A total of 300 patients with ACS who were hospitalized in the Department of Cardiology of our hospital from January 2017 to February 2018 were selected as the research objects.According to the diagnostic criteria,ACS patients were sub-grouped:acute ST segment elevation myocardial infarction group(STEMI group),acute non-ST segment elevation myocardial infarction group(NSTEMI group),unstable angina pectoris group(UA group),with 108 cases,88 cases and 104 cases in each group.100 patients with chest pain and without ACS were selected and made the non-ACS group.The clinical data of the subjects were collected and the differences of blood lipid levels among the four groups were compared.Results:The levels of total cholesterol(TC),low density lipoprotein cholesterol(LDL-C)and residual cholesterol(RC)in STEMI group,NSTEMI group and UA group were significantly higher than those in non-ACS group(P<0.05).There was no significant difference in HDL-C and non-HDL-C(P>0.05).The area under RC curve in ROC was 0.710,which was higher than other blood lipid indexes.Conclusion:RC is associated with acute coronary syndrome,and has a certain predictive value in the diagnosis of acute myocardial infarction.
作者
高腾龙
钱文茹
赵春生
马志刚
冯应强
巨名飞
GAO Tenglong;QIAN Wenru;ZHAO Chunsheng(The Affiliated Hospital of Chengde Medical College,Hebei Chengde 067000,China)
出处
《河北医学》
CAS
2021年第2期276-278,共3页
Hebei Medicine
基金
河北省承德市科学技术研究与发展计划项目,(编号:201801A026)。
关键词
总胆固醇
残余胆固醇
急性冠脉综合征
危险因素
Total cholesterol
Residual cholesterol
Acute coronary syndrome
Risk factors
