摘要
【目的】探讨SYNTAX积分评价急性冠脉综合征（Acute coronary syndrome，ACS）患者危险分层及短期预后的效能。【方法】选择2014年1月至2018年1月本院收治的210例确诊为ACS患者的临床资料，依据GRACE评分对ACS患者进行危险分层，最终将其分为低危组、中危组、高危组，每组各70例。所有患者入院后均接受PCI治疗，根据术中冠脉造影结果计算SYNTAX积分，并记录患者在院治疗期间发生不良心血管事件（MACE）情况。比较SYNTAX积分在不同危险分层患者中的差异性，分析GRACE评分与SYNTAX积分之间的相关性，同时采用受试者工作特征曲线（ROC）评价SYNTAX积分评估危险分层的效能。【结果】高危组GRACE评分、SYNTAX积分显著高于中危组、低危组，中危组GRACE积分、SYNTAX积分显著高于低危组，差异均具有统计学意义（P〈0．05）。GRACE评分与SYNTAX积分呈显著正相关性（r=0．621，P〈0.001）。将所有患者根据危险分层分为高危组（n=70）和非高危组（n=140），通过ROC曲线下面积（AUC）（95％CI）为0．82（0．76-0．87）。MACE组GRACE评分、SYNTAX积分显著高于非MACE组，差异具有统计学意义（P〈0.05）。【结论】SYNTAX积分作为评估ACS患者危险分层及预测短期预后具有重要临床意义。
[Objective]To evaluate the value of SYNTAX score for evaluation in disease risks and short-terra prognosis in acute coronary syndrome （ACS） patients.[Methods]From January 2014 to January 2018, 320 patients with ACS were recruited. According to the GRACE score, the patients with ACS were stratified at risk.Finally, 70 cases of low, medium and high risk patients were included, a total of 210 cases were studied. All patients were treated with PCI after admission. SYNTAX scores were calculated according to the results of intraoperative coronary angiography. The MACE was recorded during hospitalization. The differences of SYNTAX scores in patients with different risk stratification were compared, and the correlation between GRACE scores and SYNTAX scores was analyzed . At the same time, （ROC） was used to evaluate the value of SYNTAX score as a risk stratification evaluation index, and the relationship between SYNTAX score and MACE during hospital treatment was analyzed. [Results] The SYNTAX score of the high risk group was higher than that of the low and moderate risk groups, （11.09±2.69）, （21.58 ±5.34） and （24.89 5±6.61）. Pearson correlation analysis showed that there was a positive correlation between Grace Score and SYNTAX score （ r = 0.621）. In addition, the area under the curve （AUC） （95%CI）of ROC for identifying high-risk ACS patients with SYNTAX score was 0.82（0.76-0.87）. At the same time, the level of SYNTAX score in the MACE group was significantly higher than that in the non- MACE group （28.26 5±4.72） and （15.35 ±6.11）. The difference was statistically significant.[Conclusions]SYNTAX score as a marker for assessing risk stratification and predicting short-term prognosis in patients with ACS is of great clinical significance.
作者
王用
刘秀玲
史云桃
邢玉龙
WANG Yon;LIU Xiu-ling;SHI Yun-tao(Department of Cardiology,the Gaochun People＇s Hospital of Nanjing,Jiangsu 211300)
出处
《医学临床研究》
CAS
2018年第9期1706-1708,共3页
Journal of Clinical Research
基金
南京市医学科技发展资金资助QRX17212
