摘要
目的 探讨血脂异常痰浊阻遏证及脾肾阳虚证患者血尿酸(UA)、纤维蛋白原/白蛋白(FAR)的特点及其与中医证候程度的相关性。方法 选择2019年1月—2021年12月就诊于北京中医药大学东直门医院的血脂异常患者63例,根据中医辨证标准分为痰浊阻遏证组32例,脾肾阳虚证组31例;采集两组患者人口学资料、生命体征等基本信息,根据证候量表对入组患者证候程度进行量化评分。实验室检测入组患者UA、FAR水平。结果 (1)两组患者性别、年龄、体温、呼吸、心率、收缩压、舒张压、血脂指标比较差异均无统计学意义(均P>0.05);(2)血脂异常痰浊阻遏证患者血UA、FAR水平高于脾肾阳虚证患者,差异有统计学意义(P<0.05);(3)血脂异常痰浊阻遏证、脾肾阳虚证患者中医证候积分均与血UA水平呈正相关(P<0.05)。结论 (1)血脂异常痰浊阻遏证及脾肾阳虚证患者的血UA、FAR水平特点不同,可以反映不同证候的差异;(2)血UA水平能在一定程度上反映血脂异常痰浊阻遏证及脾肾阳虚证患者的证候严重程度;(3)上述特点与对应病证下的病因病机分析相一致,从客观指标的角度阐释了证候特点,丰富了血脂异常中医的辨证内涵。
Objective To explore the characteristics of serum uric acid(UA)and fibrinogen/albumin(FAR)in patients with dyslipidemia,phlegm turbidity suppression syndrome and spleen kidney Yang deficiency syndrome,and their correlation with the degree of traditional Chinese medicine syndrome.Methods 63 patients with dyslipidemia treated in Dongzhimen hospital of Beijing university of traditional Chinese medicine from January 2019 to December 2021 were selected. According to the syndrome differentiation standard of traditional Chinese medicine,they were divided into 32 cases of phlegm turbidity suppression syndrome group and 31 cases of spleen and kidney Yang deficiency syndrome group;The demographic data,vital signs and other basic information of the two groups were collected,and the syndrome degree of the enrolled patients was quantitatively scored according to the syndrome scale. UA and FAR levels were obtained through laboratory inspection. Results(1)There was no significant difference in gender,age,body temperature,respiration,heart rate,systolic blood pressure,diastolic blood pressure and blood lipid between the two groups(P>0.05);(2)The levels of UA and far in patients with dyslipidemia and phlegm turbidity suppression syndrome were significantly higher than those in patients with spleen and kidney Yang deficiency syndrome(P<0.05);(3)The TCM syndrome scores of patients with dyslipidemia,phlegm turbidity suppression syndrome and spleen kidney Yang deficiency syndrome were positively correlated with the level of blood UA(P<0.05). Conclusion(1)The blood UA and far levels of patients with dyslipidemia,phlegm turbidity suppression syndrome and spleen kidney Yang deficiency syndrome are different,which can reflect the differences of different syndromes;(2)The level of blood UA can reflect the severity of syndrome in patients with dyslipidemia,phlegm turbidity suppression syndrome and spleen kidney Yang deficiency syndrome to a certain extent;(3)The above characteristics are consistent with the analysis of etiology and pathoge
作者
李仰敏
杨惠民
LI Yangmin;YANG Huimin(Beijing University of Traditional Chinese Medicine,Beijing 100029,China;Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine,Beijing 100700,China)
出处
《辽宁中医药大学学报》
CAS
2023年第1期53-57,共5页
Journal of Liaoning University of Traditional Chinese Medicine
基金
国家自然科学基金青年科学基金项目(82004237)。
