摘要
目的研究糖尿病自身免疫抗体联合检测对糖尿病分型的应用效果。方法将2017年6月至2018年6月在我院确诊为糖尿病的患者100例作为观察组,同一时期在我院进行体检的无糖尿病的体检者100例作为对照组。均进行糖尿病自身免疫抗体联合检测,对患者的谷氨酸脱羧酶抗体、胰岛素自身抗体、抗胰岛素细胞抗体进行单项及联合检测,分析阳性率,并分析这些指标对不同分型糖尿病的阳性比例。结果观察组谷氨酸脱羧酶抗体、胰岛素自身抗体、抗胰岛素细胞抗体阳性率均高于对照组(P <0.05);观察组中1型糖尿病患者谷氨酸脱羧酶抗体、胰岛素自身抗体、抗胰岛素细胞抗体、三项联合阳性率均高于2型糖尿病患者(P <0.05)。结论对糖尿病患者诊断而言,糖尿病自身免疫抗体三项联合检测效果较好。
Objective To study the effect of combined detection of diabetic autoimmune antibodies on the classification of diabetes mellitus. Methods One hundred patients diagnosed with diabetes in our hospital from June 2017 to June 2018 were taken as the observation group, and 100 patients without diabetes who underwent physical examination in our hospital during the same period were used as the control group. Diabetes autoimmune antibody combined detection is carried out, and the patients’ glutamate decarboxylase antibody, insulin autoantibody, and anti-insulin cell antibody are tested individually and combined to analyze the positive rate and analyze the positive ratio of these indicators for different types of diabetes. Results The positive rates of glutamate decarboxylase antibodies, insulin autoantibodies, and anti-insulin cell antibodies in the observation group were all higher than those in the control group(P <0.05);in the observation group, glutamate decarboxylase antibodies, insulin autoantibodies, and anti-insulin were in the observation group the positive rates of cell antibody and the combination of the three items were higher than those of type 2 diabetes patients(P <0.05). Conclusion For the diagnosis of diabetes mellitus, the combined detection of diabetic autoimmune antibodies is effective, so it is worth popularizing.
作者
刘新
LIU Xin(Department of Laboratory,Huanren County People's Hospital,Benxi 117200,China)
出处
《中国医药指南》
2021年第2期124-125,共2页
Guide of China Medicine
关键词
糖尿病
分型诊断
自身免疫抗体联合检测
Diabetes mellitus
Typing diagnosis
Combined detection of autoimmune antibodies
