摘要
目的研究重症病毒性小儿脑炎联合采用丙种球蛋白和甲基强的松龙治疗的临床疗效。方法选择2017年9月—2020年2月本院90例重症病毒性小儿脑炎患儿,遵从双盲法分组标准分成两组,常规组(n=45)使用地塞米松治疗,试验组(n=45)使用丙种球蛋白+甲基强的松龙治疗。对比两组整体疗效。结果试验组总有效率高于常规组、症状改善时间短于常规组,炎性因子水平低于常规组,不良反应少于常规组,各指标对比差异具有统计学意义(P<0.05)。结论丙种球蛋白、甲基强的松龙联合运用于重症病毒性小儿脑炎治疗中疗效显著。
Objective To study the clinical efficacy of combined treatment of severe viral pediatric encephalitis with gamma globulin and methylprednisolone.Methods From September 2017 to February 2020,90 cases of severe viral pediatric encephalitis in our hospital were selected.They were divided into two groups according to the doubleblind grouping standard.The conventional group(n=45)was treated with dexamethasone.The experimental group(n=45)treatment with gamma globulin+methylprednisolone.Compare the overall efficacy of the two groups.Results The total effective rate of the experimental group was higher than the conventional group,the symptom improvement time was shorter than the conventional group,the level of inflammatory factors was lower than the conventional group,and the adverse reactions were less than the conventional group.The difference of each index was statistically significant(P<0.05).Conclusion The combination of gamma globulin and methylprednisolone is effective in the treatment of severe viral pediatric encephalitis and is worth recommending.
作者
钟宝权
ZHONG Baoquan(Department of Pediatrics,Central Hospital of Zaozhuang Mining Group,Zaozhuang Shandong 277800,China)
出处
《中国卫生标准管理》
2021年第1期85-87,共3页
China Health Standard Management
关键词
病毒性小儿脑炎
丙种球蛋白
治疗效果
炎性因子
小儿
甲基强的松龙
viral pediatric encephalitis
gamma globulin
therapeutic effect
inflammatory factors
children
methylprednisolone
