摘要
以单噁唑啉和环氧氯丙烷为原料,可以成功制备一系列结构稳定并带有可调节位阻侧链的均相固载型聚醚催化剂.固载型聚醚结构保证了催化剂能均匀地分散在大多数有机介质中,增强了其对有机底物的吸附性和配位作用,显著提高了其在有机溶剂中的催化活性.聚醚催化剂成功催化了烯烃在四氢呋喃中的不对称环氧化反应,对映选择性好,收率高(ee值高达98%,收率高达96%).此外,该聚醚催化剂可以很容易地被回收和循环使用至少10次,而催化活性不会出现显著地降低.
Based on a series of stable polyethers derived from single oxazolines and epichlorohydrins,the immobilized homogeneouscatalysts with adjustable steric hindrance of the oxazoline side chains have been successfully prepared.Polyether-immobilized structure ensures that the catalysts can be well dispersed in most of organic medium,which enhances the adsorption and coordination of organic substrate and significantly improves the reactivity in solvent.The polyether-catalysts have successfully catalyzed the asymmetric epoxidation of olefins in tetrahydrofuran with high enantio-selectivity and yield(up to 98%ee and 96%yield).Moreover,the catalysts can be easily recovered and recycled at least ten times without significant loss of catalytic activity.
作者
张安林
许慧
潘春跃
邓泽平
彭媛媛
ZHANG An-lin;XU Hui;PAN Chun-yue;DENG Ze-ping;PENG Yuan-yuan(College of Chemistry and Chemical Engineering,Central South University,Changsha 410083,China;Postdoctoral Scientific Research Cooperative R&D Center of Hunan Huateng Pharmaceutical Co.LTD,Changsha 410083,China)
出处
《分子催化》
EI
CAS
CSCD
北大核心
2020年第6期514-524,I0001,共12页
Journal of Molecular Catalysis(China)
基金
国家自然科学基金(GrantNo.21674129,21636010)
中央引导地方科技发展专项(2018CT5006)
湖南省创新创业科技投资项目(2018GK5002)。
关键词
ee值
苯乙烯
回收
不对称环氧化
聚醚
enantiomeric excess
styrene
recovery
asymmetric catalysis
polyether
